David M. Spencer

Inducible Apoptosis as a Safety Switch for Adoptive Cell Therapy

Antonio Di Stasi, Siok‐Keen Tey, Gianpietro Dotti et al. · New England Journal of Medicine · 2011 · 1.5K citations · Full text

Controlling Signal Transduction with Synthetic Ligands

David M. Spencer, Thomas J. Wandless, Stuart L. Schreiber et al. · Science · 1993 · 845 citations

Engineering, Synthetic Circuit, Cellular Physiology +17

An inducible caspase 9 safety switch for T-cell therapy

Karin Straathof, Martin Pulé, Patricia Yotnda et al. · Blood · 2005 · 719 citations · Full text

Caspase-10 is an initiator caspase in death receptor signaling

Jin Wang, Hyung J. Chun, Wilson W. Wong et al. · Proceedings of the National Academy of Sciences · 2001 · 387 citations · Full text

Inflammation, Signal Transduction, Autoimmune Disease +15

Inducible FGFR-1 Activation Leads to Irreversible Prostate Adenocarcinoma and an Epithelial-to-Mesenchymal Transition

Victor D. Acevedo, Rama Gangula, Kevin W. Freeman et al. · Cancer Cell · 2007 · 320 citations · Full text

Epithelial-to-mesenchymal Transition, Urology, Perineural Invasion +9