Concepedia

Enhancer Poising

Enhancer Poising is a regulatory state of enhancer elements in which they are transcriptionally pre-marked and maintained in a primed chromatin configuration, permitting rapid activation in response to developmental or environmental cues.

7

Publications

4.8K

Citations

65

Authors

26

Institutions

Publications per year

2017–2026

3

Parents

Publications

7

Histone H3K27ac separates active from poised enhancers and predicts developmental state

Menno P. Creyghton, Albert W. Cheng, G. Grant Welstead et al. · Proceedings of the National Academy of Sciences · 2010 · 4.5K citations · Full text

, , +17

Genome-wide dose-dependent inhibition of histone deacetylases studies reveal their roles in enhancer remodeling and suppression of oncogenic super-enhancers

Gilson J. Sanchez, Phillip A. Richmond, Eric Bunker et al. · Nucleic Acids Research · 2017 · 106 citations · Full text

, , +17

Analysis of chromatin-state plasticity identifies cell-type–specific regulators of H3K27me3 patterns

Luca Pinello, Jian Xu, Stuart H. Orkin et al. · Proceedings of the National Academy of Sciences · 2014 · 76 citations · Full text

, , +15

<i>Drosophila</i> poised enhancers are generated during tissue patterning with the help of repression

Nina Koenecke, Jeffrey Johnston, Qiye He et al. · Genome Research · 2016 · 68 citations · Full text

, , +16

Enhancer Chromatin and 3D Genome Architecture Changes from Naive to Primed Human Embryonic Stem Cell States

Stephanie L. Battle, Naresh Doni Jayavelu, Robert N. Azad et al. · Stem Cell Reports · 2019 · 40 citations · Full text

, , +17

1–5 of 7

Authors

65

  1. PM
    Piotr Mydel

    University of Bergen, Norway

    1 publications · 14 citations

    1

    h-index

  2. LP
    Luca Petiti

    Institute of Biomedical Technologies, Italy

    1 publications · 16 citations

    1

    h-index

  3. EO
    Eliah Overbey

    Cornell University, United States

    1 publications · 40 citations

    1

    h-index

  4. QZ
    Qinghong Zhang

    Chinese PLA General Hospital, China

    1 publications · 106 citations

    1

    h-index

  5. GD
    Gianluca De Bellis

    Institute of Biomedical Technologies, Italy

    1 publications · 16 citations

    1

    h-index

1–5 of 65

Institutions

26

  1. Dana-Farber Cancer Institute

    Boston, United States

    1 h-index

    4 publications

    304 citations

  2. University of Copenhagen

    Copenhagen, Denmark

    1 h-index

    4 publications

    56 citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    1 h-index

    1 publications

    76 citations

  4. Genethon (France)

    Évry-Courcouronnes, France

    1 h-index

    2 publications

    32 citations

  5. Boston Children's Hospital

    Boston, United States

    1 h-index

    2 publications

    152 citations

  6. University of Washington Medical Center

    Seattle, United States

    1 h-index

    7 publications

    280 citations

  7. National Research Council

    Rome, Italy

    1 h-index

    2 publications

    32 citations

  8. University of Bergen

    Bergen, Norway

    1 h-index

    2 publications

    28 citations

1–8 of 26

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 4.6K citations

    2

    h-index

  2. PLoS ONE

    1 publications · 16 citations

    1

    h-index

  3. Genome Research

    GR · 1 publications · 68 citations

    1

    h-index

  4. iScience

    1 publications · 14 citations

    1

    h-index

  5. Stem Cell Reports

    1 publications · 40 citations

    1

    h-index

1–5