Concepedia

Enhancer Cooperation

Enhancer Cooperation is a genomic regulatory mechanism in which multiple enhancer elements interact synergistically to augment the spatial, temporal, or quantitative precision of gene transcription beyond the additive effects of individual enhancers.

49

Publications

4.9K

Citations

317

Authors

122

Institutions

Publications per year

2017–2026

13

Variants

Synergistic Enhancer Interaction

Parents

Publications

49

Complex multi-enhancer contacts captured by genome architecture mapping

Robert A. Beagrie, Antonio Scialdone, Markus Schueler et al. · Nature · 2017 · 763 citations · Full text

, , +13

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

Klaus Giese, Chris Kingsley, Jessica R. Kirshner et al. · Genes & Development · 1995 · 543 citations · Full text

, , +17

Phase separation of ligand-activated enhancers licenses cooperative chromosomal enhancer assembly

Sreejith J. Nair, Yang Lu, Dario Meluzzi et al. · Nature Structural & Molecular Biology · 2019 · 381 citations · Full text

, , +15

Cooperativity and hierarchical levels of functional organization in the SV40 enhancer

Catherine Fromental-Ramain, Masamoto Kanno, Hisayuki Nomiyama et al. · Cell · 1988 · 240 citations

, , +12

The eve stripe 2 enhancer employs multiple modes of transcriptional synergy

David N. Arnosti, Scott Barolo, Michael Levine et al. · Development · 1996 · 232 citations

, , +15

1–5 of 49

Authors

317

  1. RJ
    Ralf Jauch

    Genome Institute of Singapore, Singapore

    2 publications · 245 citations

    2

    h-index

  2. HK
    Hisato Kondoh

    The University of Osaka, Japan

    2 publications · 77 citations

    2

    h-index

  3. TO
    Toshiya Okada

    Kyoto University, Japan

    2 publications · 77 citations

    2

    h-index

  4. MJ
    Michael J. Comb

    Cell Signaling Technology (United States), United States

    2 publications · 211 citations

    2

    h-index

  5. SE
    Steven E. Hyman

    Harvard University, United States

    2 publications · 211 citations

    2

    h-index

1–5 of 317

Institutions

122

  1. Howard Hughes Medical Institute

    Chevy Chase, United States

    4 h-index

    26 publications

    9.2K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    4 h-index

    24 publications

    1.9K citations

  3. University of Washington

    Seattle, United States

    3 h-index

    9 publications

    292 citations

  4. Genome Institute of Singapore

    Singapore, Singapore

    3 h-index

    18 publications

    3K citations

  5. University of California, San Francisco

    San Francisco, United States

    2 h-index

    14 publications

    1.8K citations

  6. Icahn School of Medicine at Mount Sinai

    New York, United States

    2 h-index

    3 publications

    497 citations

  7. Inserm

    Paris, France

    2 h-index

    13 publications

    1.2K citations

  8. University of California San Diego

    San Diego, United States

    2 h-index

    20 publications

    7K citations

1–8 of 122

Venues

  1. PLoS Genetics

    5 publications · 223 citations

    5

    h-index

  2. Molecular and Cellular Biology

    MCB · 4 publications · 288 citations

    4

    h-index

  3. Journal of Virology

    JVI · 4 publications · 381 citations

    4

    h-index

  4. The EMBO Journal

    3 publications · 454 citations

    3

    h-index

  5. Developmental Biology

    3 publications · 110 citations

    3

    h-index

1–5