Joseph Pearlberg

Rapid “Open-Source” Engineering of Customized Zinc-Finger Nucleases for Highly Efficient Gene Modification

Morgan L. Maeder, Stacey Thibodeau-Beganny, Anna Osiak et al. · Molecular Cell · 2008 · 707 citations · Full text

Engineering, Genome Surgery, Genetic Engineering +8

ErbB-3 mediates phosphoinositide 3-kinase activity in gefitinib-sensitive non-small cell lung cancer cell lines

Jeffrey A. Engelman, Pasi A. Jänne, Craig H. Mermel et al. · Proceedings of the National Academy of Sciences · 2005 · 487 citations · Full text

Tumor Microenvironment, Nsclc Cell Lines, Pi3k Associates +15

Proteins bound at adjacent DNA elements act synergistically to regulate human proenkephalin cAMP inducible transcription.

Michael J. Comb, Nicolas Mermod, Steven E. Hyman et al. · The EMBO Journal · 1988 · 342 citations · Full text

Transcriptional Regulation, Cell Regulation, Molecular Regulation +9

Differential Effects of Gefitinib and Cetuximab on Non–small-cell Lung Cancers Bearing Epidermal Growth Factor Receptor Mutations

Toru Mukohara, Jeffrey A. Engelman, Nasser H. Hanna et al. · JNCI Journal of the National Cancer Institute · 2005 · 317 citations

Contact with a component of the polymerase II holoenzyme suffices for gene activation

Alcide Barberis, Joseph Pearlberg, Natasha Simkovich et al. · Cell · 1995 · 264 citations · Full text

Transcriptional Regulation, Natural Sciences, Genetics +9