Concepedia

Author

Klaus Giese

Howard Hughes Medical Institute

Also Known As

K Giese, K. Giese, Klaus Giese

71

Publications

5.5K

Citations

24

H-Index

85

Concepts

All Affiliations

Howard Hughes Medical InstituteUniversity of California, San FranciscoMax Planck Institute for Molecular GeneticsRuhr University BochumCharité - Universitätsmedizin Berlin
KG

About

Klaus Giese is an author at Howard Hughes Medical Institute specializing in medicine, molecular biology, and natural sciences.

Top Concepts

#ConceptH-IndexPublicationsCitations

1

Medicine

15

18

3.1K

2

Natural Sciences

10

10

2K

3

Engineering

2

2

500

4

Health Sciences

2

2

40

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Public Health

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Klaus Giese

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31

Publications

4.7K

Citations

23

H-Index

YearCitations

The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structures

Klaus Giese, Jeffery S. Cox, Rudolf Grosschedl

Cell

1992

680

Structural basis for DNA bending by the architectural transcription factor LEF-1

John J. Love, Xiang Li, David A. Case,

Nature

1995

577

Assembly and function of a TCR alpha enhancer complex is dependent on LEF-1-induced DNA bending and multiple protein-protein interactions.

Klaus Giese, Chris Kingsley, Jessica R. Kirshner,

Genes & Development

1995

542

A novel siRNA-lipoplex technology for RNA interference in the mouse vascular endothelium

Ansgar Santel, Manuela Aleku, Oliver Keil,

Gene Therapy

2006

365

Atu027, a Liposomal Small Interfering RNA Formulation Targeting Protein Kinase N3, Inhibits Cancer Progression

Manuela Aleku, Petra Schulz, Oliver Keil,

Cancer Research

2008

294

DNA-binding properties of the HMG domain of the lymphoid-specific transcriptional regulator LEF-1.

Klaus Giese, Abraham Amsterdam, Rudolf Grosschedl

Genes & Development

1991

265

First-in-Human Phase I Study of the Liposomal RNA Interference Therapeutic Atu027 in Patients With Advanced Solid Tumors

Beate Schultheis, Dirk Strumberg, Ansgar Santel,

Journal of Clinical Oncology

2014

250

RNA interference in the mouse vascular endothelium by systemic administration of siRNA-lipoplexes for cancer therapy

Ansgar Santel, Manuela Aleku, Oliver Keil,

Gene Therapy

2006

184

LEF-1 contains an activation domain that stimulates transcription only in a specific context of factor-binding sites.

Klaus Giese, Rudolf Grosschedl

The EMBO Journal

1993

159

Knockdown of MTP18, a Novel Phosphatidylinositol 3-Kinase-dependent Protein, Affects Mitochondrial Morphology and Induces Apoptosis

Daniel Tondera, Ansgar Santel, Rolf Schwarzer,

Journal of Biological Chemistry

2004

140

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