Concepedia

Endolysosomal Escape Pathways

Endolysosomal Escape Pathways is a biological mechanism that enables intracellular cargo, such as nucleic acids or nanocarriers, to traverse from endolysosomal compartments into the cytosol, thereby avoiding lysosomal degradation and facilitating functional delivery within cells.

53

Publications

4.2K

Citations

349

Authors

122

Institutions

Publications per year

2017–2026

30

Parents

Publications

53

Rapid endo‐lysosomal escape of poly(DL‐lactide‐ <i>co</i> glycolide) nanoparticles: implications for drug and gene delivery

Jayanth Panyam, Wenzhong Zhou, Swayam Prabha et al. · The FASEB Journal · 2002 · 1K citations

, , +17

Nuclear Targeting Dynamics of Gold Nanoclusters for Enhanced Therapy of HER2<sup>+</sup> Breast Cancer

Yuling Wang, Jiji Chen, Joseph Irudayaraj · ACS Nano · 2011 · 259 citations

, , +17

Imaging small molecule-induced endosomal escape of siRNA

Hampus Du Rietz, Hampus Hedlund, Sten Wilhelmson et al. · Nature Communications · 2020 · 191 citations · Full text

, , +17

Ionization Behavior of Chitosan and Chitosan–DNA Polyplexes Indicate That Chitosan Has a Similar Capability to Induce a Proton-Sponge Effect as PEI

Isabelle M.T. Richard, Marc Thibault, Grégory De Crescenzo et al. · Biomacromolecules · 2013 · 190 citations

, , +15

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

John J. Chen, Diane Nathaniel, Preethi Raghavan et al. · Journal of Biological Chemistry · 2019 · 190 citations · Full text

, , +17

1–5 of 53

Authors

349

  1. JE
    Jason E. Gestwicki

    University of California, San Francisco, United States

    4 publications · 253 citations

    4

    h-index

  2. MK
    Martin Kampmann

    University of California, San Francisco, United States

    3 publications · 226 citations

    3

    h-index

  3. RT
    Ruilin Tian

    University of California, San Francisco, United States

    3 publications · 226 citations

    3

    h-index

  4. MD
    Manuel D. Leonetti

    Chan Zuckerberg Initiative (United States), United States

    3 publications · 226 citations

    3

    h-index

  5. DR
    Daniel R. Southworth

    University of California, San Francisco, United States

    3 publications · 226 citations

    3

    h-index

1–5 of 349

Institutions

122

  1. University of California, San Francisco

    San Francisco, United States

    5 h-index

    42 publications

    3K citations

  2. China Pharmaceutical University

    Nanjing, China

    4 h-index

    32 publications

    1.1K citations

  3. Institute for Neurodegenerative Disorders

    New Haven, United States

    3 h-index

    28 publications

    2.4K citations

  4. Chan Zuckerberg Initiative (United States)

    Redwood City, United States

    3 h-index

    9 publications

    678 citations

  5. National University of Singapore

    Singapore, Singapore

    2 h-index

    10 publications

    676 citations

  6. Ghent University

    Ghent, Belgium

    2 h-index

    16 publications

    1.1K citations

  7. The University of Texas Southwestern Medical Center

    Dallas, United States

    2 h-index

    16 publications

    368 citations

  8. Howard Hughes Medical Institute

    Chevy Chase, United States

    2 h-index

    2 publications

    206 citations

1–8 of 122

Venues

  1. Biomacromolecules

    4 publications · 315 citations

    4

    h-index

  2. ACS Nano

    3 publications · 408 citations

    3

    h-index

  3. Angewandte Chemie International Edition

    3 publications · 187 citations

    3

    h-index

  4. ACS Applied Materials & Interfaces

    2 publications · 74 citations

    2

    h-index

  5. Advanced Functional Materials

    2 publications · 74 citations

    2

    h-index

1–5