Concepedia

Ruilin Tian

RT

26

Publications

2.9K

Citations

19

H-Index

2014

Active since

Affiliations

University of California, San Francisco(Current)

Chan Zuckerberg Initiative (United States)

Institute for Neurodegenerative Disorders

Southern University of Science and Technology

UCSF Helen Diller Family Comprehensive Cancer Center

Ruilin Tian is an author at University of California, San Francisco specializing in medicine, cell biology, and genome editing.

Top concepts

MedicineCell BiologyCrisprGene EditingGenome EditingMolecular BiologyGeneticsGene ExpressionSystems BiologyNatural Sciences

Publications per year

2014–2025

26

Publications

26

Mitochondrial stress is relayed to the cytosol by an OMA1–DELE1–HRI pathway

Xiaoyan Guo, Giovanni Aviles, Yi Liu et al. · Nature · 2020 · 613 citations · Full text

Oma1–dele1–hri Pathway, Mitochondrial Function, Mitochondrial Dynamic +11

CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons

Ruilin Tian, Mariam A. Gachechiladze, Connor Ludwig et al. · Neuron · 2019 · 562 citations · Full text

Genome-wide CRISPRi/a screens in human neurons link lysosomal failure to ferroptosis

Ruilin Tian, Anthony Abarientos, Jason Hong et al. · Nature Neuroscience · 2021 · 390 citations · Full text

Human Neurons, Genome Instability, Molecular Neuroscience +8

Heterochromatin anomalies and double-stranded RNA accumulation underlie <i>C9orf72</i> poly(PR) toxicity

Yong‐Jie Zhang, Lin Guo, Patrick Gonzales et al. · Science · 2019 · 224 citations · Full text

Compromised function of the ESCRT pathway promotes endolysosomal escape of tau seeds and propagation of tau aggregation

John J. Chen, Diane Nathaniel, Preethi Raghavan et al. · Journal of Biological Chemistry · 2019 · 179 citations · Full text

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