Concepedia

Edaravone Therapy

Edaravone Therapy is a pharmacotherapeutic intervention, belonging to the class of neuroprotective treatments, distinguished by its mechanism of action as a free radical scavenger specifically indicated to slow functional decline in patients with amyotrophic lateral sclerosis.

391

Publications

17.5K

Citations

2.4K

Authors

637

Institutions

Publications per year

2017–2026

160

Parents

Publications

391

Safety and efficacy of edaravone in well defined patients with amyotrophic lateral sclerosis: a randomised, double-blind, placebo-controlled trial

Koji Abe, Masashi Aoki, Shoji Tsuji et al. · The Lancet Neurology · 2017 · 925 citations

, , +11

Effect of a Novel Free Radical Scavenger, Edaravone (MCI-186), on Acute Brain Infarction

Cerebrovascular Diseases · 2003 · 664 citations

, , +17

Edaravone ameliorates depressive and anxiety-like behaviors via Sirt1/Nrf2/HO-1/Gpx4 pathway

Ruozhi Dang, Mingyang Wang, Xinhui Li et al. · Journal of Neuroinflammation · 2022 · 490 citations · Full text

, , +17

Confirmatory double-blind, parallel-group, placebo-controlled study of efficacy and safety of edaravone (MCI-186) in amyotrophic lateral sclerosis patients

Koji Abe, Yasuto Itoyama, Gen Sobue et al. · Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration · 2014 · 360 citations · Full text

, , +16

Edaravone Reduces Early Accumulation of Oxidative Products and Sequential Inflammatory Responses After Transient Focal Ischemia in Mice Brain

Ning Zhang, Miki Komine‐Kobayashi, Ryota Tanaka et al. · Stroke · 2005 · 315 citations · Full text

, , +17

1–5 of 391

Authors

2.4K

  1. KA
    Kōji Abe

    Okayama University, Japan

    10 publications · 399 citations

    10

    h-index

  2. TY
    Toru Yamashita

    Okayama University, Japan

    9 publications · 316 citations

    9

    h-index

  3. KK
    Kiyoshi Kikuchi

    Kagoshima University, Japan

    7 publications · 294 citations

    7

    h-index

  4. NM
    Naoki Miura

    Kagoshima University, Japan

    7 publications · 294 citations

    7

    h-index

  5. IM
    Ikuro Maruyama

    Kagoshima University, Japan

    6 publications · 276 citations

    6

    h-index

1–5 of 2.4K

Institutions

637

  1. Okayama University

    Okayama, Japan

    16 h-index

    148 publications

    6.2K citations

  2. Mitsubishi Tanabe Pharma Corporation

    Osaka, Japan

    13 h-index

    37 publications

    2K citations

  3. Mitsubishi Corporation (United States)

    New York, United States

    11 h-index

    37 publications

    1.2K citations

  4. Kagoshima University

    Kagoshima, Japan

    8 h-index

    86 publications

    3.3K citations

  5. The University of Osaka

    Osaka, Japan

    7 h-index

    36 publications

    1.8K citations

  6. Nippon Medical School

    Tokyo, Japan

    7 h-index

    51 publications

    1.9K citations

  7. Army Medical University

    Chongqing, China

    6 h-index

    43 publications

    4.6K citations

  8. Kōchi University

    Kochi, Japan

    6 h-index

    26 publications

    765 citations

1–8 of 637

Venues

  1. European Journal of Pharmacology

    EJP · 14 publications · 781 citations

    13

    h-index

  2. 12

    h-index

  3. Journal of Stroke and Cerebrovascular Diseases

    12 publications · 301 citations

    11

    h-index

  4. Neuroscience Letters

    10 publications · 337 citations

    10

    h-index

  5. Brain Research

    9 publications · 284 citations

    10

    h-index

1–5