Ikuro Maruyama

High mobility group box 1 protein interacts with multiple Toll-like receptors

Jong Sung Park, Fabia Gamboni-Robertson, Qianbin He et al. · American Journal of Physiology-Cell Physiology · 2005 · 931 citations

Innate Immune System, Immunology, Inflammation +17

Efficacy and safety of recombinant human soluble thrombomodulin (ART‐123) in disseminated intravascular coagulation: results of a phase III, randomized, double‐blind clinical trial

Hiroaki Saito, Ikuro Maruyama, S Shimazaki et al. · Journal of Thrombosis and Haemostasis · 2006 · 594 citations

Thrombosis, Cardiovascular Disease, Medicine +8

The N-terminal domain of thrombomodulin sequesters high-mobility group-B1 protein, a novel antiinflammatory mechanism

Kazuhiro Abeyama, David M. Stern, Yuji Ito et al. · Journal of Clinical Investigation · 2005 · 518 citations · Full text

High mobility group box chromosomal protein 1 plays a role in the pathogenesis of rheumatoid arthritis as a novel cytokine

Noboru Taniguchi, Ko-ichi Kawahara, Kazunori Yone et al. · Arthritis & Rheumatism · 2003 · 472 citations

Thrombomodulin is found on endothelium of arteries, veins, capillaries, and lymphatics, and on syncytiotrophoblast of human placenta.

Ikuro Maruyama, C. Elliott Bell, Philip W. Majerus · The Journal of Cell Biology · 1985 · 414 citations · Full text

Thrombomodulin Antigen, Immunology, Blood Cell +19