Concepedia

Ebf1 Function

EBF1 Function is a molecular regulatory mechanism within the transcription factor network essential for B cell lineage commitment, distinguished by its role in activating key B cell-specific genes while repressing alternative lineage programs during early B cell development.

107

Publications

6.9K

Citations

752

Authors

238

Institutions

Publications per year

2017–2026

37

Parents

Publications

107

Failure of B-cell differentiation in mice lacking the transcription factor EBF

Haishan Lin, Rudolf Grosschedl · Nature · 1995 · 682 citations

, , +14

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

Yin C. Lin, Suchit Jhunjhunwala, Christopher Benner et al. · Nature Immunology · 2010 · 511 citations · Full text

, , +15

Transcription factor EBF1 is essential for the maintenance of B cell identity and prevention of alternative fates in committed cells

Robert Nechanitzky, Duygu Akbas, Stefanie Scherer et al. · Nature Immunology · 2013 · 234 citations

, , +13

Critical Role for Ebf1 and Ebf2 in the Adipogenic Transcriptional Cascade

M. Ángeles Jiménez, Peter Åkerblad, Mikael Sigvardsson et al. · Molecular and Cellular Biology · 2006 · 227 citations · Full text

, , +17

Ebf1 controls early cell differentiation in the embryonic striatum

Sonia Garel, Rudolf Grosschedl, Patrick Charnay · Development · 1999 · 202 citations

, , +14

1–5 of 107

Authors

752

  1. RG
    Rudolf Grosschedl

    Max Planck Institute of Immunobiology and Epigenetics, Germany

    14 publications · 1.8K citations

    13

    h-index

  2. MS
    Mikael Sigvardsson

    Lund University, Sweden

    13 publications · 1.3K citations

    12

    h-index

  3. RM
    Robert Månsson

    Karolinska Institutet, Sweden

    7 publications · 957 citations

    7

    h-index

  4. JH
    James Hagman

    National Jewish Health, United States

    6 publications · 764 citations

    6

    h-index

  5. SR
    Senthilkumar Ramamoorthy

    Max Planck Institute of Immunobiology and Epigenetics, Germany

    5 publications · 538 citations

    5

    h-index

1–5 of 752

Institutions

238

  1. Lund University

    Lund, Sweden

    12 h-index

    43 publications

    2.2K citations

  2. Max Planck Institute of Immunobiology and Epigenetics

    Freiburg, Germany

    11 h-index

    59 publications

    4.9K citations

  3. Linköping University

    Linköping, Sweden

    9 h-index

    32 publications

    2.6K citations

  4. National Jewish Health

    Denver, United States

    8 h-index

    24 publications

    1.6K citations

  5. University of Colorado Denver

    Denver, United States

    8 h-index

    25 publications

    1.6K citations

  6. Harvard University

    Cambridge, United States

    6 h-index

    16 publications

    676 citations

  7. Howard Hughes Medical Institute

    Chevy Chase, United States

    5 h-index

    13 publications

    1.9K citations

  8. University of Freiburg

    Freiburg im Breisgau, Germany

    5 h-index

    10 publications

    741 citations

1–8 of 238

Venues

  1. The Journal of Immunology

    JI · 8 publications · 486 citations

    8

    h-index

  2. Proceedings of the National Academy of Sciences

    PNAS · 7 publications · 428 citations

    7

    h-index

  3. Blood

    5 publications · 382 citations

    5

    h-index

  4. Genes & Development

    5 publications · 378 citations

    5

    h-index

  5. Nature Immunology

    4 publications · 819 citations

    4

    h-index

1–5