Inflammation Directs Memory Precursor and Short-Lived Effector CD8+ T Cell Fates via the Graded Expression of T-bet Transcription Factor

Nikhil S. Joshi, Weiguo Cui, Anmol Chandele, +5

Immunity

InflammationAutoimmune DiseaseImmune Cell DevelopmentT-regulatory CellImmunology +9

A global network of transcription factors, involving E2A, EBF1 and Foxo1, that orchestrates B cell fate

Yin C. Lin, Suchit Jhunjhunwala, Christopher Benner, +10

Nature Immunology

Systems BiologyCell RegulationB Cell FateGene RegulationGene Regulatory Network +7

Structural Insights into Histone Demethylation by JMJD2 Family Members

Zhongzhou Chen, Jianye Zang, Johnathan R. Whetstine, +11

Cell

Histone ModificationsChromatinChromatin StructureChromatin RemodelingNatural Sciences +7

Cloning and functional characterization of early B-cell factor, a regulator of lymphocyte-specific gene expression.

James Hagman, Chantal Bélanger, Adam Travis, +2

Genes & Development

Lymphocyte DevelopmentAdaptive Immune SystemImmune RegulationImmunologyImmunologic Mechanism +16

Pax-5 (BSAP) recruits Ets proto-oncogene family proteins to form functional ternary complexes on a B-cell-specific promoter.

Daniel Fitzsimmons, Wendy Hodsdon, William H. Wheat, +3

Genes & Development

GeneticsTernary Complex FormationMolecular BiologyTranscriptional RegulationProtein Expression +14

Structural Studies of Ets-1/Pax5 Complex Formation on DNA

Colin W. Garvie, James Hagman, Cynthia Wolberger

Molecular Cell

Nucleic Acid ChemistryNatural SciencesDna ReplicationMolecular BiologyEts-1/pax5 Complex Formation +1

Early B cell factor cooperates with Runx1 and mediates epigenetic changes associated with mb-1 transcription

Holly Maier, Rachel Ostraat, H. Gao, +8

Nature Immunology

Transcriptional RegulationCell RegulationMedicineGeneticsNatural Sciences +9

Opposing Functions of the ETS Factor Family Define Shh Spatial Expression in Limb Buds and Underlie Polydactyly

Laura A. Lettice, Iain Williamson, John H. Wiltshire, +9

Developmental Cell

GeneticsLimb DevelopmentCellular PhysiologySonic HedgehogTranscriptional Regulation +20

A novel lineage-specific nuclear factor regulates mb-1 gene transcription at the early stages of B cell differentiation.

James Hagman, Adam Travis, Rudolf Grosschedl

The EMBO Journal

Transcriptional RegulationLineage PlasticityCell LineageEarly StagesCell Regulation +10

An inhibitory carboxyl-terminal domain in Ets-1 and Ets-2 mediates differential binding of ETS family factors to promoter sequences of the mb-1 gene.

James Hagman, Rudolf Grosschedl

Proceedings of the National Academy of Sciences

GeneticsImmunologyMolecular BiologyMb-1 Gene ExpressionTranscriptional Regulation +19