Concepedia

Diablo Release

DIABLO Release is a molecular mechanism denoting the mitochondrial release of the second mitochondria-derived activator of caspases (SMAC)/DIABLO protein, which functions to promote apoptosis by antagonizing inhibitor of apoptosis proteins (IAPs) during apoptosome assembly.

34

Publications

2.4K

Citations

174

Authors

75

Institutions

Publications per year

2017–2026

1

Variants

Smac Release

Parents

Publications

34

Apoptosis‐associated release of Smac/DIABLO from mitochondria requires active caspases and is blocked by Bcl‐2

Colin Adrain · The EMBO Journal · 2001 · 436 citations · Full text

, , +14

Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.

Karthikeyan Kandasamy, Srinivasa M. Srinivasula, Emad S. Alnemri et al. · PubMed · 2003 · 196 citations

, , +17

Rapid Kinetics of tBid-induced Cytochrome c and Smac/DIABLO Release and Mitochondrial Depolarization

Muniswamy Madesh, Bruno Antonsson, Srinivasa M. Srinivasula et al. · Journal of Biological Chemistry · 2002 · 183 citations · Full text

, , +17

Activation of ERK1/2 protects melanoma cells from TRAIL-induced apoptosis by inhibiting Smac/DIABLO release from mitochondria

Xu Dong Zhang, Jodie M. Borrow, Xi Yi Zhang et al. · Oncogene · 2003 · 164 citations

, , +16

Real-time single cell analysis of Smac/DIABLO release during apoptosis

Markus Rehm, Heiko Düßmann, Jochen H.M. Prehn · The Journal of Cell Biology · 2003 · 151 citations · Full text

, , +17

1–5 of 34

Authors

174

  1. SG
    Steven Grant

    Virginia Commonwealth University, United States

    4 publications · 157 citations

    4

    h-index

  2. YD
    Yun Dai

    Virginia Commonwealth University, United States

    3 publications · 132 citations

    3

    h-index

  3. ES
    Emad S. Alnemri

    Thomas Jefferson University, United States

    2 publications · 379 citations

    2

    h-index

  4. SM
    Srinivasa M. Srinivasula

    Thomas Jefferson University, United States

    2 publications · 379 citations

    2

    h-index

  5. PD
    Paul Dent

    Virginia Commonwealth University, United States

    2 publications · 66 citations

    2

    h-index

1–5 of 174

Institutions

75

  1. Virginia Commonwealth University Medical Center

    Richmond, United States

    3 h-index

    5 publications

    179 citations

  2. St. Jude Children's Research Hospital

    Memphis, United States

    2 h-index

    6 publications

    237 citations

  3. University of Manitoba

    Winnipeg, Canada

    2 h-index

    8 publications

    635 citations

  4. University Hospital Münster

    Münster, Germany

    2 h-index

    4 publications

    574 citations

  5. Japan Science and Technology Agency

    Tokyo, Japan

    1 h-index

    3 publications

    45 citations

  6. University of Urbino

    Urbino, Italy

    1 h-index

    6 publications

    84 citations

  7. University of California, Los Angeles

    Los Angeles, United States

    1 h-index

    7 publications

    497 citations

  8. Virginia Commonwealth University

    Richmond, United States

    1 h-index

    1 publications

    38 citations

1–8 of 75

Venues

  1. Journal of Biological Chemistry

    JBC · 4 publications · 345 citations

    4

    h-index

  2. PubMed

    Repository · 4 publications · 322 citations

    4

    h-index

  3. Oncogene

    2 publications · 211 citations

    2

    h-index

  4. APOPTOSIS

    2 publications · 44 citations

    2

    h-index

  5. Cell Death and Differentiation

    CDD · 2 publications · 68 citations

    2

    h-index

1–5