Concepedia

Computational Variant Prediction

Computational Variant Prediction is a scholarly methodological contribution that employs algorithmic, statistical, or machine learning approaches to infer the functional or clinical impact of genetic variants, distinguished from other variant classification strategies by its reliance on in silico modeling rather than empirical or population-based evidence.

203

Publications

29.9K

Citations

1.2K

Authors

610

Institutions

Publications per year

2017–2026

128

Parents

Publications

203

Predicting the effects of coding non-synonymous variants on protein function using the SIFT algorithm

P. Naresh Kumar, Steven Henikoff, Pauline C. Ng · Nature Protocols · 2009 · 6.7K citations

, , +15

CADD: predicting the deleteriousness of variants throughout the human genome

Philipp Rentzsch, Daniela Witten, Gregory M. Cooper et al. · Nucleic Acids Research · 2018 · 3.9K citations · Full text

, , +17

Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models

Hashem A. Shihab, Julian Gough, D.N. Cooper et al. · Human Mutation · 2012 · 1.4K citations · Full text

, , +16

Predicting the insurgence of human genetic diseases associated to single point protein mutations with support vector machines and evolutionary information

Emidio Capriotti, Remo Calabrese, Rita Casadio · Bioinformatics · 2006 · 968 citations · Full text

, , +14

SNAP: predict effect of non-synonymous polymorphisms on function

Yana Bromberg, Burkhard Rost · Nucleic Acids Research · 2007 · 876 citations · Full text

, , +15

1–5 of 203

Authors

1.2K

  1. MV
    Mauno Vihinen

    9 publications · 922 citations

    9

    h-index

  2. EC
    Emidio Capriotti

    University of Bologna, Italy

    8 publications · 1.9K citations

    8

    h-index

  3. JA
    Joseph A. Marsh

    University of Edinburgh, United Kingdom

    7 publications · 630 citations

    7

    h-index

  4. DC
    D.N. Cooper

    Cardiff University, United Kingdom

    7 publications · 3K citations

    7

    h-index

  5. YB
    Yana Bromberg

    Rutgers, The State University of New Jersey, United States

    7 publications · 2K citations

    7

    h-index

1–5 of 1.2K

Institutions

610

  1. Inserm

    Paris, France

    12 h-index

    33 publications

    1.7K citations

  2. University of Edinburgh

    Edinburgh, United Kingdom

    10 h-index

    22 publications

    1.8K citations

  3. Lund University

    Lund, Sweden

    9 h-index

    16 publications

    1.4K citations

  4. Harvard University

    Cambridge, United States

    8 h-index

    33 publications

    5.8K citations

  5. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    45 publications

    1.7K citations

  6. Broad Institute

    Cambridge, United States

    8 h-index

    26 publications

    3.4K citations

  7. University of Bologna

    Bologna, Italy

    7 h-index

    15 publications

    3.4K citations

  8. Cardiff University

    Cardiff, United Kingdom

    7 h-index

    13 publications

    5.7K citations

1–8 of 610

Venues

  1. Human Mutation

    22 publications · 2.7K citations

    18

    h-index

  2. Nucleic Acids Research

    13 publications · 6.2K citations

    13

    h-index

  3. Scientific Reports

    13 publications · 764 citations

    11

    h-index

  4. Bioinformatics

    8 publications · 1.3K citations

    8

    h-index

  5. PLoS ONE

    6 publications · 435 citations

    6

    h-index

1–5