Hashem A. Shihab

The MR-Base platform supports systematic causal inference across the human phenome

Gibran Hemani, Jie Zheng, Benjamin Elsworth et al. · eLife · 2018 · 8K citations · Full text

Predicting the Functional, Molecular, and Phenotypic Consequences of Amino Acid Substitutions using Hidden Markov Models

Hashem A. Shihab, Julian Gough, D.N. Cooper et al. · Human Mutation · 2012 · 1.4K citations · Full text

Genetics, Molecular Biology, Amino Acid Substitutions +26

An integrative approach to predicting the functional effects of non-coding and coding sequence variation

Hashem A. Shihab, Mark F. Rogers, Julian Gough et al. · Bioinformatics · 2015 · 724 citations · Full text

Systematic identification of genetic influences on methylation across the human life course

Tom R. Gaunt, Hashem A. Shihab, Gibran Hemani et al. · Genome biology · 2016 · 614 citations · Full text

FATHMM-XF: accurate prediction of pathogenic point mutations via extended features

Mark F. Rogers, Hashem A. Shihab, Matthew Mort et al. · Bioinformatics · 2017 · 521 citations · Full text