Concepedia

Computational Target Selection

Comput膳ional Target Selection is a computational methodology within multi-target drug design that identifies and prioritizes biological targets by integrating molecular, network, and phenotypic data to maximize therapeutic efficacy and minimize off-target effects.

46

Publications

3K

Citations

360

Authors

124

Institutions

Publications per year

2017–2026

16

Parents

Publications

46

IntaRNA: efficient prediction of bacterial sRNA targets incorporating target site accessibility and seed regions

Anke Busch, Andreas S. Richter, Rolf Backofen · Bioinformatics · 2008 · 561 citations · Full text

, , +13

Prioritizing Candidate Disease miRNAs by Topological Features in the miRNA Target–Dysregulated Network: Case Study of Prostate Cancer

Juan Xu, Chuanxing Li, Jun-Ying Lv et al. · Molecular Cancer Therapeutics · 2011 · 233 citations

, , +17

Identification of pyruvate kinase type M2 as potential oncoprotein in squamous cell carcinoma of tongue through microRNA profiling

Thian‐Sze Wong, Xiaobing Liu, Ambrose Chung‐Wai Ho et al. · International Journal of Cancer · 2008 · 190 citations · Full text

, , +16

New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao et al. · Journal of Medicinal Chemistry · 2012 · 185 citations

, , +17

Antiviral effects of probiotic metabolites on COVID-19

Firoz Anwar, Hisham N. Altayb, Fahad A. Al‐Abbasi et al. · Journal of Biomolecular Structure and Dynamics · 2020 · 150 citations · Full text

, , +16

1–5 of 46

Authors

360

  1. PS
    Petra Schneider

    ETH Zurich, Switzerland

    3 publications · 119 citations

    3

    h-index

  2. GS
    Gisbert Schneider

    ETH Zurich, Switzerland

    3 publications · 119 citations

    3

    h-index

  3. DR
    Daniel Reker

    ETH Zurich, Switzerland

    2 publications · 79 citations

    2

    h-index

  4. XL
    Xia Li

    Harbin Medical University, China

    2 publications · 252 citations

    2

    h-index

  5. RB
    Rolf Backofen

    University of Freiburg, Germany

    2 publications · 665 citations

    2

    h-index

1–5 of 360

Institutions

124

  1. University of Freiburg

    Freiburg im Breisgau, Germany

    4 h-index

    20 publications

    3.4K citations

  2. University of Basel

    Basel, Switzerland

    3 h-index

    4 publications

    145 citations

  3. ETH Zurich

    Zurich, Switzerland

    3 h-index

    12 publications

    476 citations

  4. Bayer (Germany)

    Leverkusen, Germany

    2 h-index

    3 publications

    123 citations

  5. Harbin Medical University

    Harbin, China

    2 h-index

    22 publications

    3.2K citations

  6. Heidelberg University

    Heidelberg, Germany

    2 h-index

    15 publications

    915 citations

  7. University of California, San Francisco

    San Francisco, United States

    2 h-index

    3 publications

    160 citations

  8. Second Military Medical University

    Shanghai, China

    2 h-index

    17 publications

    1.8K citations

1–8 of 124

Venues

  1. PLoS ONE

    3 publications · 83 citations

    3

    h-index

  2. Chemical Communications

    ChemComm · 2 publications · 79 citations

    2

    h-index

  3. Bioinformatics

    2 publications · 665 citations

    2

    h-index

  4. RNA Biology

    2 publications · 102 citations

    2

    h-index

  5. Journal of Medicinal Chemistry

    2 publications · 210 citations

    2

    h-index

1–5