Concepedia

Compound Library Prioritization

Compound Library Prioritization is a systematic method in cheminformatics that ranks collections of chemical compounds according to their potential utility in drug discovery, distinguished by the integration of multi-parametric criteria such as diversity, drug-likeness, and target specificity to optimize screening efficiency.

93

Publications

4.8K

Citations

608

Authors

241

Institutions

Publications per year

2017–2026

24

Parents

Publications

93

Natural Product-likeness Score and Its Application for Prioritization of Compound Libraries

Peter Ertl, Silvio Roggo, Ansgar Schuffenhauer · Journal of Chemical Information and Modeling · 2007 · 413 citations

, , +17

Development of a Virtual Screening Method for Identification of “Frequent Hitters” in Compound Libraries

Olivier Roche, Petra Schneider, Jochen Zuegge et al. · Journal of Medicinal Chemistry · 2001 · 250 citations

, , +16

Application of a High-Content Multiparameter Cytotoxicity Assay to Prioritize Compounds Based on Toxicity Potential in Humans

Vivek C. Abraham, Danli L. Towne, Jeffrey F. Waring et al. · SLAS DISCOVERY · 2008 · 148 citations · Full text

, , +17

Molecular Docking Screens Using Comparative Models of Proteins

Hao Fan, John J. Irwin, Benjamin Webb et al. · Journal of Chemical Information and Modeling · 2009 · 137 citations · Full text

, , +14

Drug-like Index:  A New Approach To Measure Drug-like Compounds and Their Diversity

Jun Xu, James Stevenson · Journal of Chemical Information and Computer Sciences · 2000 · 135 citations

, , +14

1–5 of 93

Authors

608

  1. JB
    Jürgen Bajorath

    University of Bonn, Germany

    5 publications · 107 citations

    5

    h-index

  2. SE
    Sean Ekins

    Collaborations Pharmaceuticals (United States), United States

    3 publications · 135 citations

    3

    h-index

  3. DA
    Darren A. N. Cook

    Liverpool School of Tropical Medicine, United Kingdom

    2 publications · 159 citations

    2

    h-index

  4. AS
    Ansgar Schuffenhauer

    Novartis (Switzerland), Switzerland

    2 publications · 470 citations

    2

    h-index

  5. TR
    Thomas R. Lane

    Collaborations Pharmaceuticals (United States), United States

    2 publications · 64 citations

    2

    h-index

1–5 of 608

Institutions

241

  1. University of Bonn

    Bonn, Germany

    6 h-index

    14 publications

    379 citations

  2. National Institutes of Health

    Bethesda, United States

    4 h-index

    29 publications

    1.2K citations

  3. National Center for Advancing Translational Sciences

    Rockville, United States

    4 h-index

    16 publications

    524 citations

  4. Novartis (United States)

    New York, United States

    3 h-index

    12 publications

    465 citations

  5. Collaborations Pharmaceuticals (United States)

    Raleigh, United States

    3 h-index

    13 publications

    455 citations

  6. University of Toronto

    Toronto, Canada

    3 h-index

    19 publications

    799 citations

  7. Indiana University – Purdue University Indianapolis

    Indianapolis, United States

    3 h-index

    8 publications

    192 citations

  8. Scripps Research Institute

    San Diego, United States

    3 h-index

    6 publications

    162 citations

1–8 of 241

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 18 publications · 1K citations

    14

    h-index

  2. 7

    h-index

  3. Journal of Medicinal Chemistry

    5 publications · 575 citations

    5

    h-index

  4. SLAS DISCOVERY

    3 publications · 337 citations

    3

    h-index

  5. PLoS ONE

    3 publications · 123 citations

    3

    h-index

1–5