Concepedia

Complex Disease Genetics

Complex Disease Genetics is a subfield of population genetics in medicine that focuses on the identification and analysis of genetic and environmental factors contributing to diseases influenced by multiple genes and non-Mendelian inheritance patterns, distinguished from monogenic disease genetics by its emphasis on polygenic, epistatic, and multifactorial etiologies.

686

Publications

42.4K

Citations

4.9K

Authors

1.4K

Institutions

Publications per year

2017–2026

131

Parents

Publications

686

RNA splicing is a primary link between genetic variation and disease

Yang Li, Bryce van de Geijn, Anil Raj et al. · Science · 2016 · 772 citations · Full text

, , +16

Heterogeneity testing in meta‐analysis of genome searches

John P. A. Ioannidis · Genetic Epidemiology · 2004 · 704 citations

, , +12

Most Rare Missense Alleles Are Deleterious in Humans: Implications for Complex Disease and Association Studies

Gregory V. Kryukov, L Pennacchio, Shamil Sunyaev · The American Journal of Human Genetics · 2007 · 607 citations · Full text

, , +14

Recent Explosive Human Population Growth Has Resulted in an Excess of Rare Genetic Variants

Alon Keinan, Andrew G. Clark · Science · 2012 · 602 citations

, , +13

Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology

Elizabeth J. Rossin, Kasper Lage, Soumya Raychaudhuri et al. · PLoS Genetics · 2011 · 464 citations · Full text

, , +17

1–5 of 686

Authors

4.9K

  1. MD
    Marylyn D. Ritchie

    Vanderbilt University, United States

    10 publications · 1.1K citations

    10

    h-index

  2. JL
    Jonathan L. Haines

    University of Miami, United States

    9 publications · 1.1K citations

    9

    h-index

  3. JH
    Jason H. Moore

    Dartmouth College, United States

    9 publications · 628 citations

    9

    h-index

  4. NR
    Naomi R. Wray

    The University of Queensland, Australia

    8 publications · 858 citations

    8

    h-index

  5. MJ
    Mark J. Daly

    Broad Institute, United States

    8 publications · 1K citations

    8

    h-index

1–5 of 4.9K

Institutions

1.4K

  1. Harvard University

    Cambridge, United States

    30 h-index

    120 publications

    14.5K citations

  2. Brigham and Women's Hospital

    Boston, United States

    24 h-index

    58 publications

    5.9K citations

  3. University of Oxford

    Oxford, United Kingdom

    22 h-index

    50 publications

    4.5K citations

  4. Broad Institute

    Cambridge, United States

    22 h-index

    168 publications

    23.4K citations

  5. National Institutes of Health

    Bethesda, United States

    20 h-index

    87 publications

    7.5K citations

  6. Center for Human Genetics

    Bar Harbor, United States

    20 h-index

    93 publications

    11.8K citations

  7. University of California, San Francisco

    San Francisco, United States

    20 h-index

    48 publications

    2.8K citations

  8. University College London

    London, United Kingdom

    16 h-index

    52 publications

    3.1K citations

1–8 of 1.4K

Venues

  1. Human Molecular Genetics

    31 publications · 3.1K citations

    27

    h-index

  2. PLoS ONE

    35 publications · 2.1K citations

    23

    h-index

  3. PubMed

    Repository · 39 publications · 1.4K citations

    21

    h-index

  4. PLoS Genetics

    15 publications · 2.7K citations

    15

    h-index

  5. The American Journal of Human Genetics

    AJHG · 13 publications · 2K citations

    13

    h-index

1–5