Concepedia

Complement-mediated Thromboinflammation

Complement-Mediated Thromboinflammation is a pathophysiological process characterized by the dysregulated activation of the complement system that drives concurrent thrombotic and inflammatory responses, primarily through endothelial injury, platelet activation, and leukocyte recruitment, thereby linking innate immunity with microvascular thrombosis in conditions such as thrombotic microangiopathies, sepsis, and ischemia-reperfusion injury.

42

Publications

3.2K

Citations

264

Authors

102

Institutions

Publications per year

2017–2026

23

Parents

Publications

42

Immune complement and coagulation dysfunction in adverse outcomes of SARS-CoV-2 infection

Vijendra Ramlall, Phyllis Thangaraj, Cem Meydan et al. · Nature Medicine · 2020 · 368 citations · Full text

, , +17

Thrombus formation induced by antibodies to β2-glycoprotein I is complement dependent and requires a priming factor

Fabio Fischetti, Paolo Durigutto, Valentina Pellis et al. · Blood · 2005 · 353 citations · Full text

, , +16

Cytokine and complement levels in patients undergoing cardiopulmonary bypass

John B. Steinberg, David P. Kapelanski, John D. Olson et al. · Journal of Thoracic and Cardiovascular Surgery · 1993 · 307 citations

, , +11

Inhibition of Thrombin Abrogates the Instant Blood-Mediated Inflammatory Reaction Triggered by Isolated Human Islets

Lisa Özmen, Kristina Nilsson Ekdahl, Graciela Elgue et al. · Diabetes · 2002 · 265 citations

, , +15

Heparin-Associated Thrombocytopenia

Douglas B. Cines, Paul Kaywin, Mahin Bina et al. · New England Journal of Medicine · 1980 · 261 citations

, , +11

1–5 of 42

Authors

264

  1. TE
    Tom Eirik Mollnes

    Oslo University Hospital, Norway

    6 publications · 267 citations

    6

    h-index

  2. JD
    John D. Lambris

    University of Pennsylvania, United States

    6 publications · 259 citations

    6

    h-index

  3. TM
    Trent M. Woodruff

    The University of Queensland, Australia

    4 publications · 103 citations

    4

    h-index

  4. OB
    Ole‐Lars Brekke

    Nordland Hospital, Norway

    3 publications · 88 citations

    3

    h-index

  5. JK
    Judith Krey Ludviksen

    Nordland Hospital, Norway

    3 publications · 63 citations

    3

    h-index

1–5 of 264

Institutions

102

  1. Oslo University Hospital

    Oslo, Norway

    8 h-index

    22 publications

    996 citations

  2. University of Oslo

    Oslo, Norway

    7 h-index

    14 publications

    513 citations

  3. Nordland Hospital

    Bodø, Norway

    7 h-index

    20 publications

    654 citations

  4. University of Pennsylvania

    Philadelphia, United States

    7 h-index

    13 publications

    1K citations

  5. Norwegian University of Science and Technology

    Trondheim, Norway

    6 h-index

    11 publications

    340 citations

  6. UiT The Arctic University of Norway

    Tromsø, Norway

    5 h-index

    17 publications

    428 citations

  7. Linnaeus University

    Vaxjo, Sweden

    4 h-index

    10 publications

    470 citations

  8. The University of Queensland

    Brisbane, Australia

    4 h-index

    4 publications

    103 citations

1–8 of 102

Venues

  1. Frontiers in Immunology

    6 publications · 250 citations

    6

    h-index

  2. Blood

    5 publications · 825 citations

    5

    h-index

  3. The Journal of Immunology

    JI · 4 publications · 134 citations

    4

    h-index

  4. Journal of Thrombosis and Haemostasis

    JTH · 3 publications · 192 citations

    3

    h-index

  5. Journal of Surgical Research

    JSR · 2 publications · 60 citations

    2

    h-index

1–5