Concepedia

Complement Regulator Targeting

Complement Regulator Targeting is a therapeutic strategy within complement-targeted therapy that specifically modulates the activity of endogenous complement regulatory proteins to control excessive or dysregulated complement activation in disease contexts.

53

Publications

3K

Citations

327

Authors

112

Institutions

Publications per year

2017–2026

9

Parents

Publications

53

Human complement regulatory proteins protect swine-to-primate cardiac xenografts from humoral injury

Kenneth R. McCurry, David L. Kooyman, Cristobal G. Alvarado et al. · Nature Medicine · 1995 · 540 citations

, , +14

A Novel Sialic Acid Binding Site on Factor H Mediates Serum Resistance of Sialylated <i>Neisseria gonorrhoeae </i>

Sanjay Ram, Ajay Sharma, Scott D. Simpson et al. · The Journal of Experimental Medicine · 1998 · 401 citations · Full text

, , +16

Rational Engineering of a Minimized Immune Inhibitor with Unique Triple-Targeting Properties

Christoph Q. Schmidt, Hongjun Bai, Zhuoer Lin et al. · The Journal of Immunology · 2013 · 133 citations · Full text

, , +17

NMR studies of a viral protein that mimics the regulators of complement activation

Alan P. Wiles, Graeme L. Shaw, Jeremy R. Bright et al. · Journal of Molecular Biology · 1997 · 123 citations

, , +15

Lipoplex mediated silencing of membrane regulators (CD46, CD55 and CD59) enhances complement‐dependent anti‐tumor activity of trastuzumab and pertuzumab

Srinivas Mamidi, Marc Cinci, Max Hasmann et al. · Molecular Oncology · 2013 · 110 citations · Full text

, , +17

1–5 of 53

Authors

327

  1. BP
    B. Paul Morgan

    Cardiff University, United Kingdom

    7 publications · 281 citations

    7

    h-index

  2. MK
    Michael Kirschfink

    Heidelberg University, Germany

    5 publications · 346 citations

    5

    h-index

  3. ST
    Stephen Tomlinson

    Medical University of South Carolina, United States

    4 publications · 111 citations

    4

    h-index

  4. CL
    Claire L. Harris

    Cardiff University, United Kingdom

    4 publications · 158 citations

    4

    h-index

  5. AS
    Anwen S. Williams

    Cardiff University, United Kingdom

    4 publications · 209 citations

    4

    h-index

1–5 of 327

Institutions

112

  1. Heidelberg University

    Heidelberg, Germany

    6 h-index

    25 publications

    1.6K citations

  2. University of Wales

    Cardiff, United Kingdom

    5 h-index

    14 publications

    628 citations

  3. Medical University of South Carolina

    Charleston, United States

    4 h-index

    10 publications

    271 citations

  4. Cardiff University

    Cardiff, United Kingdom

    4 h-index

    6 publications

    148 citations

  5. Washington University in St. Louis

    St Louis, United States

    4 h-index

    20 publications

    336 citations

  6. Leibniz-Institut für Naturstoff-Forschung und Infektionsbiologie e. V. - Hans-Knöll-Institut (HKI)

    Jena, Germany

    4 h-index

    10 publications

    810 citations

  7. Duke Medical Center

    Durham, United States

    3 h-index

    14 publications

    2.3K citations

  8. University of Freiburg

    Freiburg im Breisgau, Germany

    3 h-index

    27 publications

    965 citations

1–8 of 112

Venues

  1. PubMed

    Repository · 5 publications · 83 citations

    5

    h-index

  2. The Journal of Immunology

    JI · 4 publications · 195 citations

    4

    h-index

  3. Journal of Biological Chemistry

    JBC · 3 publications · 122 citations

    3

    h-index

  4. Blood

    2 publications · 134 citations

    2

    h-index

  5. Clinical & Experimental Immunology

    CEI · 2 publications · 110 citations

    2

    h-index

1–5