Concepedia

Comparative Binding Site Analysis

Comparative Binding Site Analysis is a computational method that identifies and evaluates structurally conserved regions across multiple protein binding sites to infer pharmacophoric features critical for ligand recognition and binding specificity.

96

Publications

5.5K

Citations

388

Authors

171

Institutions

Publications per year

2017–2026

15

Parents

Publications

96

Two disparate ligand-binding sites in the human P2Y1 receptor

Dandan Zhang, Zhan‐Guo Gao, Kaihua Zhang et al. · Nature · 2015 · 370 citations · Full text

, , +14

A comparative study of the binding modes of recently launched dipeptidyl peptidase IV inhibitors in the active site

Mika Nabeno, Fumihiko Akahoshi, Hiroyuki Kishida et al. · Biochemical and Biophysical Research Communications · 2013 · 304 citations

, , +16

Comparison of the Binding of Reversible Inhibitors to Human Butyrylcholinesterase and Acetylcholinesterase: A Crystallographic, Kinetic and Calorimetric Study

Terrone L. Rosenberry, Xavier Brazzolotto, Ian R. Macdonald et al. · Molecules · 2017 · 293 citations · Full text

, , +17

Do Structurally Similar Ligands Bind in a Similar Fashion?

Jonas Boström, Anders Hogner, Stefan Schmitt · Journal of Medicinal Chemistry · 2006 · 178 citations

, , +15

PocketMatch: A new algorithm to compare binding sites in protein structures

Kalidas Yeturu, Nagasuma Chandra · BMC Bioinformatics · 2008 · 162 citations · Full text

, , +10

1–5 of 96

Authors

388

  1. NC
    Nagasuma Chandra

    Indian Institute of Science Bangalore, India

    5 publications · 264 citations

    5

    h-index

  2. RM
    Richard M. Jackson

    University of Leeds, United Kingdom

    4 publications · 243 citations

    4

    h-index

  3. CE
    Christiane Ehrt

    Universität Hamburg, Germany

    4 publications · 247 citations

    4

    h-index

  4. GC
    Gabriele Cruciani

    University of Perugia, Italy

    3 publications · 148 citations

    3

    h-index

  5. LS
    Lydia Siragusa

    Molecular Discovery (United Kingdom), United Kingdom

    3 publications · 148 citations

    3

    h-index

1–5 of 388

Institutions

171

  1. Indian Institute of Science Bangalore

    Bengaluru, India

    5 h-index

    10 publications

    528 citations

  2. University of Perugia

    Perugia, Italy

    4 h-index

    9 publications

    417 citations

  3. University of Leeds

    Leeds, United Kingdom

    4 h-index

    10 publications

    528 citations

  4. TU Dortmund University

    Dortmund, Germany

    3 h-index

    9 publications

    699 citations

  5. Molecular Discovery (United Kingdom)

    London, United Kingdom

    3 h-index

    6 publications

    296 citations

  6. Université de Strasbourg

    Strasbourg, France

    3 h-index

    4 publications

    335 citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    7 publications

    657 citations

  8. University of Oxford

    Oxford, United Kingdom

    3 h-index

    12 publications

    206 citations

1–8 of 171

Venues

  1. Journal of Chemical Information and Modeling

    JCIM · 13 publications · 661 citations

    12

    h-index

  2. Proteins Structure Function and Bioinformatics

    9 publications · 528 citations

    9

    h-index

  3. Bioinformatics

    6 publications · 220 citations

    6

    h-index

  4. Journal of Medicinal Chemistry

    4 publications · 359 citations

    4

    h-index

  5. PLoS Computational Biology

    4 publications · 188 citations

    4

    h-index

1–5