Concepedia

Combination Therapy Development

Combination Therapy Development is a research methodology in drug development that involves the systematic design and evaluation of multiple therapeutic agents to achieve enhanced efficacy, reduced resistance, or improved safety compared to monotherapies.

42

Publications

2.4K

Citations

250

Authors

133

Institutions

Publications per year

2017–2026

15

Parents

Publications

42

Systems biology and combination therapy in the quest for clinical efficacy

Jonathan B. Fitzgerald, Birgit Schoeberl, Ulrik B. Nielsen et al. · Nature Chemical Biology · 2006 · 583 citations

, , +16

Combination Therapies for Traumatic Brain Injury: Prospective Considerations

Susan S. Margulies, Ramona Hicks · Journal of Neurotrauma · 2009 · 296 citations · Full text

, , +10

Development of Novel Combination Therapies

Janet Woodcock, Joseph P. Griffin, Rachel E. Behrman · New England Journal of Medicine · 2011 · 247 citations

, , +8

Structure-guided combination therapy to potently improve the function of mutant CFTRs

Guido Veit, Haijin Xu, Elise Dréano et al. · Nature Medicine · 2018 · 139 citations

, , +11

Project IDentif.AI: Harnessing Artificial Intelligence to Rapidly Optimize Combination Therapy Development for Infectious Disease Intervention

Aynur Abdulla, Boqian Wang, Qian Feng et al. · Advanced Therapeutics · 2020 · 65 citations · Full text

, , +15

1–5 of 42

Authors

250

  1. SS
    Susan S. Margulies

    University of Pennsylvania, United States

    3 publications · 382 citations

    3

    h-index

  2. RH
    Ramona Hicks

    University of Kentucky, United States

    2 publications · 318 citations

    2

    h-index

  3. SK
    Scott Kopetz

    The University of Texas MD Anderson Cancer Center, United States

    1 publications · 10 citations

    1

    h-index

  4. FG
    F-D Goebel

    University College London, United Kingdom

    1 publications · 22 citations

    1

    h-index

  5. RN
    Ronak N. Shah

    University of Toronto, Canada

    1 publications · 36 citations

    1

    h-index

1–5 of 250

Institutions

133

  1. University of Pennsylvania

    Philadelphia, United States

    3 h-index

    3 publications

    382 citations

  2. Ludwig-Maximilians-Universität München

    Munich, Germany

    3 h-index

    3 publications

    82 citations

  3. University of Pittsburgh

    Pittsburgh, United States

    2 h-index

    5 publications

    203 citations

  4. Inserm

    Paris, France

    2 h-index

    4 publications

    439 citations

  5. National Institute of Neurological Disorders and Stroke

    Bethesda, United States

    2 h-index

    2 publications

    318 citations

  6. Boston University

    Boston, United States

    2 h-index

    4 publications

    101 citations

  7. Johns Hopkins University

    Baltimore, United States

    2 h-index

    5 publications

    96 citations

  8. Dana-Farber Cancer Institute

    Boston, United States

    2 h-index

    9 publications

    102 citations

1–8 of 133

Venues

  1. PubMed

    Repository · 7 publications · 154 citations

    7

    h-index

  2. Journal of Neurotrauma

    3 publications · 382 citations

    3

    h-index

  3. New England Journal of Medicine

    NEJM · 2 publications · 302 citations

    2

    h-index

  4. Cancer Chemotherapy and Pharmacology

    2 publications · 23 citations

    2

    h-index

  5. Acta Pharmacologica Sinica

    APS · 1 publications · 48 citations

    1

    h-index

1–5