Design of therapeutic proteins with enhanced stability

Naresh Chennamsetty, Vladimir Voynov, Veysel Kayser, +2

Proceedings of the National Academy of Sciences

Protein ChemistryEngineeringTherapeutic AntibodiesProtein FoldingMedicine +13

Developability Index: A Rapid In Silico Tool for the Screening of Antibody Aggregation Propensity

Timothy M. Lauer, Neeraj J. Agrawal, Naresh Chennamsetty, +3

Journal of Pharmaceutical Sciences

Translational MedicineImmunocytochemical TechniqueAllergyMedicineBioanalysis +13

Prediction of Aggregation Prone Regions of Therapeutic Proteins

Naresh Chennamsetty, Vladimir Voynov, Veysel Kayser, +2

The Journal of Physical Chemistry B

Glycosylation influences on the aggregation propensity of therapeutic monoclonal antibodies

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, +3

Biotechnology Journal

Aggregation-Prone Motifs in Human Immunoglobulin G

Naresh Chennamsetty, Bernhard Helk, Vladimir Voynov, +2

Journal of Molecular Biology

ImmunogeneticsHuman Immunoglobulin GAutoimmune DiseaseImmunologyAutoimmunity +5

Economics of recombinant antibody production processes at various scales: Industry‐standard compared to continuous precipitation

Nikolaus Hammerschmidt, Anne Tscheließnig, Ralf J. Sommer, +2

Biotechnology Journal

Computational tool for the early screening of monoclonal antibodies for their viscosities

Neeraj J. Agrawal, Bernhard Helk, Sandeep Kumar, +6

mAbs

Immunocytochemical TechniqueEngineeringImmunologyComputational ToolBiomedical Engineering +23

Evaluation of a Non-Arrhenius Model for Therapeutic Monoclonal Antibody Aggregation

Veysel Kayser, Naresh Chennamsetty, Vladimir Voynov, +3

Journal of Pharmaceutical Sciences

Translational MedicineImmunocytochemical TechniqueAutoimmune DiseaseNon-arrhenius ModelMedicine +9

Predictive tools for stabilization of therapeutic proteins

Vladimir Voynov, Naresh Chennamsetty, Veysel Kayser, +2

mAbs

Protein AssemblyMolecular BiologyProtein FoldingAntibody EngineeringProtein Stabilization +14

Enabling Low Cost Biopharmaceuticals: A Systematic Approach to Delete Proteases from a Well-Known Protein Production Host Trichoderma reesei

Christopher P. Landowski, Anne Huuskonen, Ramon Wahl, +10

PLoS ONE

Protein SecretionImmunologyGlycobiologyMolecular BiologyEnzymatic Modification +15