Concepedia

Cofactor Activation

Cofactor Activation is a biochemical mechanism within enzyme activation whereby an enzymatically inactive apoenzyme is converted into an active holoenzyme through the binding of a non-protein cofactor molecule essential for its catalytic function.

128

Publications

7.6K

Citations

529

Authors

180

Institutions

Publications per year

2017–2026

12

Parents

Publications

128

The Structural Biology of Expression and Function of Tissue Factor

Thomas S. Edgington, Nigel Mackman, Korbinian Brand et al. · Thrombosis and Haemostasis · 1991 · 556 citations

, , +17

Some Characteristics of the Enzymic Lipid Peroxidation System in the Microsomal Fraction of Flounder Skeletal Muscle

R. E. McDonald, Herbert O. Hultin · Journal of Food Science · 1987 · 323 citations

, , +17

Staphylocoagulase is a prototype for the mechanism of cofactor-induced zymogen activation

Rainer W. Friedrich, Peter Panizzi, Pablo Fuentes‐Prior et al. · Nature · 2003 · 260 citations

, , +9

New cofactor supports α,β-unsaturated acid decarboxylation via 1,3-dipolar cycloaddition

K.A.P. Payne, Mark D. White, Karl Fisher et al. · Nature · 2015 · 258 citations · Full text

, , +12

Characteristics of the cofactor requirements for the superoxide-generating NADPH oxidase of human polymorphonuclear leukocytes

David R. Light, Angela M. O'Callaghan, Edward J. Goetzl et al. · Biochemistry · 1981 · 248 citations

, , +17

1–5 of 128

Authors

529

  1. WR
    Wolfram Ruf

    Scripps Research Institute, United States

    3 publications · 620 citations

    3

    h-index

  2. SN
    Shigeharu Nagasawa

    Hokkaido University, Japan

    3 publications · 247 citations

    3

    h-index

  3. JP
    Judith P. Klinman

    University of California, Berkeley, United States

    2 publications · 93 citations

    2

    h-index

  4. WL
    Wolfgang Lubitz

    Max Planck Institute for Chemical Energy Conversion, Germany

    2 publications · 91 citations

    2

    h-index

  5. ME
    Michael E. Nesheim

    Queen's University, Canada

    2 publications · 157 citations

    2

    h-index

1–5 of 529

Institutions

180

  1. University of Wisconsin–Madison

    Madison, United States

    4 h-index

    13 publications

    392 citations

  2. University of Southern California

    Los Angeles, United States

    4 h-index

    11 publications

    215 citations

  3. Scripps Research Institute

    San Diego, United States

    3 h-index

    8 publications

    2.4K citations

  4. Uppsala University

    Uppsala, Sweden

    3 h-index

    8 publications

    329 citations

  5. Max Planck Institute of Biochemistry

    Martinsried, Germany

    3 h-index

    10 publications

    1.8K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    3 h-index

    13 publications

    345 citations

  7. Northwestern University

    Evanston, United States

    3 h-index

    10 publications

    1.7K citations

  8. Harvard University

    Cambridge, United States

    3 h-index

    9 publications

    701 citations

1–8 of 180

Venues

  1. Journal of Biological Chemistry

    JBC · 17 publications · 950 citations

    16

    h-index

  2. Biochemistry

    15 publications · 888 citations

    14

    h-index

  3. Biochemical Journal

    BJ · 5 publications · 207 citations

    5

    h-index

  4. PubMed

    Repository · 4 publications · 150 citations

    4

    h-index

  5. Science

    4 publications · 581 citations

    4

    h-index

1–5