Concepedia

Codon-based Ancestral Reconstruction

Codon-Based Ancestral Reconstruction is a computational method in phylogenetics that infers ancestral protein-coding sequences at codon level by integrating nucleotide substitution models with amino acid constraints to reconstruct evolutionary histories with greater biological realism than nucleotide- or amino acid-only approaches.

6

Publications

482

Citations

22

Authors

11

Institutions

Publications per year

2017–2026

1

Parents

Publications

6

Recreating a Functional Ancestral Archosaur Visual Pigment

Belinda S. W. Chang, Karolina Jönsson, Manija A. Kazmi et al. · Molecular Biology and Evolution · 2002 · 165 citations

, , +17

Evaluating placental inter-ordinal phylogenies with novel sequences including RAG1, γ-fibrinogen, ND6, and mt-tRNA, plus MCMC-driven nucleotide, amino acid, and codon models

Peter J. Waddell, Shawn Shelley · Molecular Phylogenetics and Evolution · 2003 · 115 citations

, , +14

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction

Philip M. Zakas, Harrison C. Brown, Kristopher A. Knight et al. · Nature Biotechnology · 2016 · 109 citations

, , +14

Sequence fossils, triplet expansion, and reconstruction of earliest codons

E. N. Trifonov, Thomas Bettecken · Gene · 1997 · 63 citations

, , +16

Patterns of Ancestral Animal Codon Usage Bias Revealed through Holozoan Protists

Jade Southworth, Paul Armitage, Brandon Fallon et al. · Molecular Biology and Evolution · 2018 · 19 citations · Full text

, , +14

1–5 of 6

Authors

22

  1. PM
    Philip M. Zakas

    Emory University, United States

    1 publications · 109 citations

    1

    h-index

  2. JS
    Jade Southworth

    University of Huddersfield, United Kingdom

    1 publications · 19 citations

    1

    h-index

  3. KJ
    Karolina Jönsson

    Rockefeller University, United States

    1 publications · 165 citations

    1

    h-index

  4. SL
    Shannon L. Meeks

    Emory University, United States

    1 publications · 109 citations

    1

    h-index

  5. HD
    Holly Dawson

    University of Huddersfield, United Kingdom

    1 publications · 19 citations

    1

    h-index

1–5 of 22

Institutions

11

  1. University of Wyoming

    Laramie, United States

    1 h-index

    1 publications

    115 citations

  2. Emory University

    Atlanta, United States

    1 h-index

    6 publications

    654 citations

  3. Aflac (United States)

    Columbus, United States

    1 h-index

    4 publications

    436 citations

  4. University of Huddersfield

    Huddersfield, United Kingdom

    1 h-index

    6 publications

    114 citations

  5. Georgia Institute of Technology

    Atlanta, United States

    1 h-index

    1 publications

    109 citations

  6. University of South Carolina

    Columbia, United States

    1 h-index

    1 publications

    115 citations

  7. Weizmann Institute of Science

    Rehovot, Israel

    1 h-index

    1 publications

    63 citations

  8. National Institute of Genetics

    Mishima, Japan

    1 h-index

    1 publications

    11 citations

1–8 of 11

Venues

  1. Molecular Biology and Evolution

    MBE · 2 publications · 184 citations

    2

    h-index

  2. Gene

    1 publications · 63 citations

    1

    h-index

  3. Nature Biotechnology

    1 publications · 109 citations

    1

    h-index

  4. Journal of Molecular Evolution

    1 publications · 11 citations

    1

    h-index

  5. Molecular Phylogenetics and Evolution

    1 publications · 115 citations

    1

    h-index

1–5