Shannon L. Meeks

De novo mutations across 1,465 diverse genomes reveal mutational insights and reductions in the Amish founder population

Michael D. Kessler, Douglas P. Loesch, James A. Perry et al. · Proceedings of the National Academy of Sciences · 2020 · 112 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction

Philip M. Zakas, Harrison C. Brown, Kristopher A. Knight et al. · Nature Biotechnology · 2016 · 109 citations

Life Sciences, Bioinformatics, Pharmacology +14

A microengineered vascularized bleeding model that integrates the principal components of hemostasis

Yumiko Sakurai, Elaissa T. Hardy, Byungwook Ahn et al. · Nature Communications · 2018 · 100 citations · Full text

Medicine, Biomedical Engineering, Hematology +17

Antihuman factor VIII C2 domain antibodies in hemophilia A mice recognize a functionally complex continuous spectrum of epitopes dominated by inhibitors of factor VIII activation

Shannon L. Meeks, John F. Healey, Ernest T. Parker et al. · Blood · 2007 · 91 citations · Full text

Life Sciences, Hematology, Immunology +12

Resolving the multifaceted mechanisms of the ferric chloride thrombosis model using an interdisciplinary microfluidic approach

Jordan C. Ciciliano, Yumiko Sakurai, David R. Myers et al. · Blood · 2015 · 85 citations · Full text

Engineering, Bioengineering, Biomedical Engineering +16