Kristopher A. Knight

Enhancing the pharmaceutical properties of protein drugs by ancestral sequence reconstruction

Philip M. Zakas, Harrison C. Brown, Kristopher A. Knight et al. · Nature Biotechnology · 2016 · 107 citations · Full text

Protein Drugs, Drug Repositioning, Drug Target +13

Development of chimeric antigen receptors targeting T-cell malignancies using two structurally different anti-CD5 antigen binding domains in NK and CRISPR-edited T cell lines

Sunil S. Raikar, Lauren Fleischer, Robert Moot et al. · OncoImmunology · 2017 · 86 citations · Full text

Car Expression, Car T Cells, Radiation Oncology +15

Ex vivo expanded patient-derived γδ T-cell immunotherapy enhances neuroblastoma tumor regression in a murine model

Jaquelyn T. Zoine, Kristopher A. Knight, Lauren Fleischer et al. · OncoImmunology · 2019 · 38 citations · Full text

Cell Therapy, Immunology, Immune Regulation +18

Effects of FVIII immunity on hepatocyte and hematopoietic stem cell–directed gene therapy of murine hemophilia A

Allison M. Lytle, Harrison C. Brown, Na Yoon Paik et al. · Molecular Therapy — Methods & Clinical Development · 2016 · 24 citations · Full text

Histocompatibility, Cell Therapy, Immune Regulation +24

The Spleen and Organized Lymph Nodes Are Not Essential for the Development of Gut-Induced Mucosal Immune Responses in Lymphotoxin-α Deficient Mice

Ila A. Davis, Kristopher A. Knight, B. T. Rouse · Clinical Immunology and Immunopathology · 1998 · 17 citations

Inflammation, Lymphotoxin-α Deficient Mice, Mucosal Immunology +11