Concepedia

Codon Usage Optimization

Codon Usage Optimization is a computational or experimental method in synthetic biology that systematically adjusts the frequency of synonymous codons in a coding sequence to enhance gene expression efficiency, accuracy, or other translational outcomes in a given organism or context.

547

Publications

38.1K

Citations

2.6K

Authors

812

Institutions

Publications per year

2017–2026

145

Parents

Publications

547

JCat: a novel tool to adapt codon usage of a target gene to its potential expression host

Andreas Grote, Karsten Hiller, Maurice Scheer et al. · Nucleic Acids Research · 2005 · 1.6K citations · Full text

, , +13

Removal of a cryptic intron and subcellular localization of green fluorescent protein are required to mark transgenic <i>Arabidopsis</i> plants brightly

Jim Haseloff, Kirby Siemering, Douglas C. Prasher et al. · Proceedings of the National Academy of Sciences · 1997 · 1.3K citations · Full text

, , +13

Codon catalog usage is a genome strategy modulated for gene expressivity

Richard Grantham, Christian Gautier, Manolo Gouy et al. · Nucleic Acids Research · 1981 · 951 citations · Full text

, , +13

OPTIMIZER: a web server for optimizing the codon usage of DNA sequences

Pere Puigbò, Efrain Guzman, A. Romeu et al. · Nucleic Acids Research · 2007 · 620 citations · Full text

, , +13

A "humanized" green fluorescent protein cDNA adapted for high-level expression in mammalian cells

Sergei Zolotukhin, Mark Potter, William W. Hauswirth et al. · Journal of Virology · 1996 · 614 citations · Full text

, , +17

1–5 of 547

Authors

2.6K

  1. RW
    Ralf Wagner

    University of Regensburg, Germany

    10 publications · 981 citations

    10

    h-index

  2. SC
    Supriyo Chakraborty

    Assam University, India

    8 publications · 332 citations

    8

    h-index

  3. AU
    Arif Uddin

    Assam University, India

    8 publications · 318 citations

    8

    h-index

  4. MG
    Marcus Graf

    University of Regensburg, Germany

    7 publications · 810 citations

    7

    h-index

  5. MZ
    Mian Zhou

    Feinstein Institute for Medical Research, United States

    6 publications · 1.2K citations

    6

    h-index

1–5 of 2.6K

Institutions

812

  1. Chinese Academy of Agricultural Sciences

    Beijing, China

    15 h-index

    117 publications

    4.1K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    24 publications

    1K citations

  3. National Institutes of Health

    Bethesda, United States

    10 h-index

    57 publications

    2.6K citations

  4. Assam University

    Silchar, India

    10 h-index

    27 publications

    923 citations

  5. Chinese Academy of Sciences

    Beijing, China

    9 h-index

    44 publications

    1.4K citations

  6. Harvard University

    Cambridge, United States

    9 h-index

    21 publications

    2.4K citations

  7. University of Regensburg

    Regensburg, Germany

    9 h-index

    33 publications

    3.4K citations

  8. Jiangnan University

    Wuxi, China

    8 h-index

    40 publications

    1.6K citations

1–8 of 812

Venues

  1. Protein Expression and Purification

    23 publications · 1.3K citations

    19

    h-index

  2. Journal of Virology

    JVI · 21 publications · 3K citations

    18

    h-index

  3. Nucleic Acids Research

    20 publications · 5K citations

    18

    h-index

  4. PLoS ONE

    21 publications · 874 citations

    16

    h-index

  5. Gene

    14 publications · 692 citations

    14

    h-index

1–5