Concepedia

Chromosome Amplification

Chromosome Amplification is a genetic engineering technique that belongs to the class of chromosome manipulation methods, distinguished by its deliberate increase in the copy number of specific chromosomes or chromosomal regions within a cell to achieve enhanced gene expression or functional genomics analysis.

70

Publications

3.8K

Citations

328

Authors

148

Institutions

Publications per year

2017–2026

7

Parents

Publications

70

Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification

Hermann‐Josef Lüdecke, Gabriele Senger, Uwe Claussen et al. · Nature · 1989 · 333 citations

, , +13

A central role for chromosome breakage in gene amplification, deletion formation, and amplicon integration.

B E Windle, Bruce W. Draper, Yue-Qi Yin et al. · Genes & Development · 1991 · 248 citations · Full text

, , +17

An international study of intrachromosomal amplification of chromosome 21 (iAMP21): cytogenetic characterization and outcome

Christine J. Harrison, Anthony V. Moorman, Claire Schwab et al. · Leukemia · 2013 · 197 citations

, , +17

A method for the rapid sequence-independent amplification of microdissected chromosomal material

Stefan K. Bohlander, Rafael Espinosa, Michelle M. Le Beau et al. · Genomics · 1992 · 182 citations

, , +9

Renal mucinous tubular and spindle carcinoma lacks the gains of chromosomes 7 and 17 and losses of chromosome Y that are prevalent in papillary renal cell carcinoma

Paolo Cossu‐Rocca, John N. Eble, Brett Delahunt et al. · Modern Pathology · 2006 · 148 citations · Full text

, , +12

1–5 of 70

Authors

328

  1. AL
    A. Lima-de-Faria

    Lund University, Sweden

    6 publications · 174 citations

    6

    h-index

  2. HJ
    Halina Jaworska

    Lund University, Sweden

    4 publications · 95 citations

    4

    h-index

  3. GM
    Geoffrey M. Wahl

    Salk Institute for Biological Studies, United States

    4 publications · 523 citations

    4

    h-index

  4. OL
    O. L. Miller

    Oak Ridge National Laboratory, United States

    2 publications · 61 citations

    2

    h-index

  5. AA
    Alberto Abbondandolo

    University of Pisa, Italy

    2 publications · 30 citations

    2

    h-index

1–5 of 328

Institutions

148

  1. Lund University

    Lund, Sweden

    6 h-index

    14 publications

    436 citations

  2. Salk Institute for Biological Studies

    La Jolla, United States

    4 h-index

    10 publications

    1.8K citations

  3. Whitehead Institute for Biomedical Research

    Cambridge, United States

    3 h-index

    8 publications

    379 citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    3 h-index

    8 publications

    285 citations

  5. Harvard University

    Cambridge, United States

    3 h-index

    6 publications

    153 citations

  6. The Honourable Society of Lincoln's Inn

    London, United Kingdom

    2 h-index

    6 publications

    271 citations

  7. National Cancer Institute

    Bethesda, United States

    2 h-index

    2 publications

    46 citations

  8. Johns Hopkins University

    Baltimore, United States

    2 h-index

    4 publications

    264 citations

1–8 of 148

Venues

  1. Molecular and Cellular Biology

    MCB · 9 publications · 378 citations

    9

    h-index

  2. Hereditas

    6 publications · 174 citations

    6

    h-index

  3. Cancer Genetics and Cytogenetics

    3 publications · 74 citations

    3

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 3 publications · 74 citations

    3

    h-index

  5. PLoS ONE

    3 publications · 95 citations

    3

    h-index

1–5