Cloning defined regions of the human genome by microdissection of banded chromosomes and enzymatic amplification

DNA sequencing with chain-terminating inhibitors

Frederick Sanger, S. Nicklen, Alan Coulson · Proceedings of the National Academy of Sciences · 1977 · 69.3K citations · Full text

Life Sciences, Microbiology, Molecular Biology +10

Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia

Randall K. Saiki, Stephen J. Scharf, Fred Faloona et al. · Science · 1985 · 9K citations

Medicine, Genetics, Molecular Genetics +17

Mendelian Inheritance in Man

P. S Harper · Journal of Medical Genetics · 1987 · 581 citations · Full text

Life Sciences, Genetics, Molecular Genetics +6

Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion.

Louis M. Kunkel, Anthony P. Monaco, William Middlesworth et al. · Proceedings of the National Academy of Sciences · 1985 · 453 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Microdissection and cloning of DNA from a specific region of Drosophila melanogaster polytene chromosomes

Franco Scalenghe, E Turco, J.-E. Edström et al. · Chromosoma · 1981 · 343 citations

Life Sciences, Genetics, Molecular Biology +13