Concepedia

Chromosomal Amplifications

Chromosomal Amplification is a cytogenetic aberration characterized by the presence of multiple copies of a specific genomic region, typically resulting in oncogene overexpression and contributing to tumorigenesis.

534

Publications

37K

Citations

3.2K

Authors

820

Institutions

Publications per year

2017–2026

37

Variants

Chromosomal Amplification

Parents

Publications

534

onc gene amplification in promyelocytic leukaemia cell line HL-60 and primary leukaemic cells of the same patient

Riccardo Dalla Favera, Flossie Wong‐Staal, Robert C. Gallo · Nature · 1982 · 637 citations

, , +17

Extrachromosomal DNA is associated with oncogene amplification and poor outcome across multiple cancers

Hoon Kim, Nam Nguyen, Kristen M. Turner et al. · Nature Genetics · 2020 · 635 citations · Full text

, , +15

Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage

Nature Biotechnology · 2011 · 595 citations · Full text

, , +12

ERBB2 amplification in breast cancer analyzed by fluorescence in situ hybridization.

Olli Kallioniemi, Anne Kallioniemi, Wayne Kurisu et al. · Proceedings of the National Academy of Sciences · 1992 · 560 citations

, , +15

Loss of heterozygosity on chromosomes 3, 13, and 17 in small-cell carcinoma and on chromosome 3 in adenocarcinoma of the lung.

Jun Yokota, M Wada, Yukío Shimosato et al. · Proceedings of the National Academy of Sciences · 1987 · 489 citations · Full text

, , +13

1–5 of 534

Authors

3.2K

  1. GM
    Geoffrey M. Wahl

    Salk Institute for Biological Studies, United States

    12 publications · 1.3K citations

    12

    h-index

  2. JI
    Johji Inazawa

    Tokyo Medical and Dental University, Japan

    13 publications · 914 citations

    12

    h-index

  3. AK
    Anne Kallioniemi

    9 publications · 1.7K citations

    9

    h-index

  4. PL
    Peter Lichter

    German Cancer Research Center, Germany

    9 publications · 854 citations

    9

    h-index

  5. II
    Issei Imoto

    Tokyo Medical and Dental University, Japan

    9 publications · 610 citations

    9

    h-index

1–5 of 3.2K

Institutions

820

  1. Lund University

    Lund, Sweden

    19 h-index

    83 publications

    6K citations

  2. Inserm

    Paris, France

    16 h-index

    74 publications

    6K citations

  3. Centre National de la Recherche Scientifique

    Paris, France

    15 h-index

    52 publications

    3K citations

  4. German Cancer Research Center

    Heidelberg, Germany

    15 h-index

    64 publications

    6.8K citations

  5. Tokyo Medical and Dental University

    Tokyo, Japan

    14 h-index

    51 publications

    3.6K citations

  6. National Institutes of Health

    Bethesda, United States

    13 h-index

    54 publications

    7.1K citations

  7. University of California, San Francisco

    San Francisco, United States

    13 h-index

    60 publications

    8.9K citations

  8. National Cancer Institute

    Bethesda, United States

    12 h-index

    54 publications

    5K citations

1–8 of 820

Venues

  1. PubMed

    Repository · 66 publications · 6.7K citations

    45

    h-index

  2. Genes Chromosomes and Cancer

    80 publications · 4.9K citations

    44

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 20 publications · 2.6K citations

    19

    h-index

  4. Cancer Genetics and Cytogenetics

    23 publications · 877 citations

    18

    h-index

  5. Molecular and Cellular Biology

    MCB · 15 publications · 675 citations

    14

    h-index

1–5