Concepedia

Cellular Response Profiling

Cellular Response Profiling is a systematic analytical approach in chemical genomics that characterizes the phenotypic and molecular changes in cells exposed to bioactive compounds, thereby distinguishing itself by enabling the functional annotation of compounds and target pathways through comprehensive, high-throughput measurement of cellular states.

987

Publications

66.9K

Citations

6.8K

Authors

1.6K

Institutions

Publications per year

2017–2026

374

Parents

Children

Publications

987

Genomics of Drug Sensitivity in Cancer (GDSC): a resource for therapeutic biomarker discovery in cancer cells

Wanjuan Yang, Jorge Soares, Patricia Greninger et al. · Nucleic Acids Research · 2012 · 4.3K citations · Full text

, , +17

oncoPredict: an R package for predicting <i>in vivo</i> or cancer patient drug response and biomarkers from cell line screening data

Danielle Maeser, Robert F. Gruener, R. Stephanie Huang · Briefings in Bioinformatics · 2021 · 1.7K citations · Full text

, , +13

CellMiner: A Web-Based Suite of Genomic and Pharmacologic Tools to Explore Transcript and Drug Patterns in the NCI-60 Cell Line Set

William C. Reinhold, Margot Sunshine, Hongfang Liu et al. · Cancer Research · 2012 · 931 citations · Full text

, , +17

Harnessing Connectivity in a Large-Scale Small-Molecule Sensitivity Dataset

Brinton Seashore‐Ludlow, Matthew G. Rees, Jaime H. Cheah et al. · Cancer Discovery · 2015 · 888 citations · Full text

, , +14

Global mapping of binding sites for Nrf2 identifies novel targets in cell survival response through ChIP-Seq profiling and network analysis

Deepti Malhotra, Élodie Portales-Casamar, Anju Singh et al. · Nucleic Acids Research · 2010 · 781 citations · Full text

, , +17

1–5 of 987

Authors

6.8K

  1. TA
    Tero Aittokallio

    University of Helsinki, Finland

    13 publications · 1.4K citations

    13

    h-index

  2. KW
    Krister Wennerberg

    Institute for Molecular Medicine Finland, Finland

    14 publications · 1.4K citations

    13

    h-index

  3. RJ
    Richard Judson

    Environmental Protection Agency, United States

    11 publications · 1K citations

    11

    h-index

  4. KA
    Keith A. Houck

    Environmental Protection Agency, United States

    9 publications · 972 citations

    9

    h-index

  5. BH
    Benjamin Haibe‐Kains

    Princess Margaret Cancer Centre, Canada

    8 publications · 498 citations

    8

    h-index

1–5 of 6.8K

Institutions

1.6K

  1. Harvard University

    Cambridge, United States

    31 h-index

    190 publications

    40.4K citations

  2. National Institutes of Health

    Bethesda, United States

    26 h-index

    166 publications

    22.3K citations

  3. University of Helsinki

    Helsinki, Finland

    23 h-index

    173 publications

    20K citations

  4. Broad Institute

    Cambridge, United States

    21 h-index

    189 publications

    45.1K citations

  5. Environmental Protection Agency

    Washington, United States

    20 h-index

    130 publications

    12.1K citations

  6. Centre National de la Recherche Scientifique

    Paris, France

    20 h-index

    108 publications

    6.9K citations

  7. Research Triangle Park Foundation

    Durham, United States

    19 h-index

    127 publications

    12.2K citations

  8. University of Toronto

    Toronto, Canada

    18 h-index

    96 publications

    7.6K citations

1–8 of 1.6K

Venues

  1. PLoS ONE

    50 publications · 3K citations

    27

    h-index

  2. Toxicological Sciences

    24 publications · 1.7K citations

    23

    h-index

  3. SLAS DISCOVERY

    37 publications · 1.7K citations

    22

    h-index

  4. Scientific Reports

    35 publications · 1.9K citations

    22

    h-index

  5. Nature Communications

    29 publications · 2K citations

    22

    h-index

1–5