Concepedia

Compound Sensitivity Profiling

Compound Sensitivity Profiling is a systematic experimental approach that quantitatively measures the phenotypic responses of cellular systems to chemical compounds, distinguished by its focus on characterizing the differential susceptibility of biological models across diverse compound perturbations to inform drug efficacy and toxicity.

34

Publications

2.1K

Citations

274

Authors

110

Institutions

Publications per year

2017–2026

10

Parents

Publications

34

Chemosensitivity prediction by transcriptional profiling

Jane Staunton, Donna K. Slonim, Hilary A. Coller et al. · Proceedings of the National Academy of Sciences · 2001 · 688 citations

, , +13

Quantitative scoring of differential drug sensitivity for individually optimized anticancer therapies

Bhagwan Yadav, Tea Pemovska, Agnieszka Szwajda et al. · Scientific Reports · 2014 · 369 citations · Full text

, , +16

Basis for natural variation in sensitivity to 5-fluorouracil in mouse and human cells in culture.

Jeffrey D. Laskin, Ronald M. Evans, Harry K. Slocum et al. · PubMed · 1979 · 104 citations

, , +15

Discovery of novel drug sensitivities in T-PLL by high-throughput ex vivo drug testing and mutation profiling

Emma Andersson, S. Pützer, Bhagwan Yadav et al. · Leukemia · 2017 · 97 citations

, , +15

A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins

François M.M van Och, Wout Slob, Wim H. de Jong et al. · Toxicology · 2000 · 88 citations

, , +14

1–5 of 34

Authors

274

  1. OK
    Olli Kallioniemi

    University of Helsinki, Finland

    3 publications · 528 citations

    3

    h-index

  2. TP
    Tea Pemovska

    University of Helsinki, Finland

    2 publications · 466 citations

    2

    h-index

  3. WR
    William R. Sellers

    Dana-Farber Cancer Institute, United States

    2 publications · 74 citations

    2

    h-index

  4. BY
    Bhagwan Yadav

    University of Helsinki, Finland

    2 publications · 466 citations

    2

    h-index

  5. KW
    Krister Wennerberg

    Institute for Molecular Medicine Finland, Finland

    2 publications · 466 citations

    2

    h-index

1–5 of 274

Institutions

110

  1. Harvard University

    Cambridge, United States

    5 h-index

    29 publications

    9.6K citations

  2. Institute for Molecular Medicine Finland

    Helsinki, Finland

    3 h-index

    30 publications

    6.3K citations

  3. University of Helsinki

    Helsinki, Finland

    3 h-index

    35 publications

    6.8K citations

  4. Dana-Farber Cancer Institute

    Boston, United States

    3 h-index

    18 publications

    9.2K citations

  5. Heidelberg University

    Heidelberg, Germany

    2 h-index

    30 publications

    2K citations

  6. Harvard University Press

    Cambridge, United States

    2 h-index

    2 publications

    730 citations

  7. Brigham and Women's Hospital

    Boston, United States

    2 h-index

    2 publications

    73 citations

  8. Broad Institute

    Cambridge, United States

    2 h-index

    15 publications

    710 citations

1–8 of 110

Venues

  1. International Journal of Cancer

    2 publications · 65 citations

    2

    h-index

  2. British Journal of Cancer

    BJC · 2 publications · 71 citations

    2

    h-index

  3. Scientific Reports

    2 publications · 411 citations

    2

    h-index

  4. Proceedings of the National Academy of Sciences

    PNAS · 2 publications · 719 citations

    2

    h-index

  5. Genome biology

    2 publications · 56 citations

    2

    h-index

1–5