François M.M van Och

A quantitative method for assessing the sensitizing potency of low molecular weight chemicals using a local lymph node assay: employment of a regression method that includes determination of the uncertainty margins

François M.M van Och, Wout Slob, Wim H. de Jong et al. · Toxicology · 2000 · 88 citations

Medicine, Pharmacology, Dose-response Modeling +14

Cytokine Production Induced by Low-Molecular-Weight Chemicals as a Function of the Stimulation Index in a Modified Local Lymph Node Assay: An Approach to Discriminate Contact Sensitizers from Respiratory Sensitizers

François M.M van Och, Henk Van Loveren, Wim H. de Jong et al. · Toxicology and Applied Pharmacology · 2002 · 73 citations

Life Sciences, Immunology, Toxicology +17

Assessment of potency of allergenic activity of low molecular weight compounds based on IL-1α and IL-18 production by a murine and human keratinocyte cell line

François M.M van Och, Henk Van Loveren, Josien C. van Wolfswinkel et al. · Toxicology · 2005 · 60 citations

Life Sciences, Dermatology, Immunology +11

Comparison of three different in vitro mutation assays used for the investigation of cytochrome P450-mediated mutagenicity of nitro-polycyclic aromatic hydrocarbons

Wendela A. Kappers, François M.M van Och, Els M. de Groene et al. · Mutation Research/Genetic Toxicology and Environmental Mutagenesis · 2000 · 27 citations

Pharmacy, Genetics, Toxicology +16

Effect of prolonged exposure to low antigen concentration for sensitization

François M.M van Och, Rob J. Vandebriel, Wim H. de Jong et al. · Toxicology · 2002 · 16 citations

Life Sciences, Immunology, Allergy +13