Concepedia

Cellular Context Dependence

Cellular Context Dependence is a theoretical construct in molecular biology that denotes the phenomenon whereby the functional outcome of death receptor signaling is determined by the specific cellular environment, including expression levels of regulatory proteins, cell type, and concurrent signaling pathways, thereby distinguishing it from intrinsic or universally deterministic models of apoptosis regulation.

347

Publications

23.3K

Citations

2.2K

Authors

680

Institutions

Publications per year

2017–2026

117

Parents

Publications

347

ERβ: Identification and characterization of a novel human estrogen receptor

Sietse Mosselman, Jan Polman, R. Dijkema · FEBS Letters · 1996 · 2.3K citations · Full text

, , +15

Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq

Mariella G. Filbin, Itay Tirosh, Volker Hovestadt et al. · Science · 2018 · 736 citations · Full text

, , +17

Tumor induction by an endogenous K-ras oncogene is highly dependent on cellular context

Carmen Guerra, Nieves Mijimolle, Alma Dhawahir et al. · Cancer Cell · 2003 · 572 citations · Full text

, , +16

STAT3 Target Genes Relevant to Human Cancers

Richard L. Carpenter, Hui‐Wen Lo · Cancers · 2014 · 532 citations · Full text

, , +15

Deep learning of the tissue-regulated splicing code

Michael K. K. Leung, Hui Xiong, Leo J. Lee et al. · Bioinformatics · 2014 · 487 citations · Full text

, , +13

1–5 of 347

Authors

2.2K

  1. LB
    Lawrence Bogorad

    Harvard University, United States

    4 publications · 417 citations

    4

    h-index

  2. DA
    Douglas A. Lauffenburger

    Massachusetts Institute of Technology, United States

    3 publications · 122 citations

    3

    h-index

  3. MF
    Mónika Fuxreiter

    University of Debrecen, Hungary

    3 publications · 131 citations

    3

    h-index

  4. YZ
    Yujia Zhou

    Nanchang University, China

    2 publications · 35 citations

    2

    h-index

  5. BT
    Basile Tessier‐Cloutier

    University of British Columbia, Canada

    2 publications · 121 citations

    2

    h-index

1–5 of 2.2K

Institutions

680

  1. Harvard University

    Cambridge, United States

    22 h-index

    94 publications

    19.8K citations

  2. University of California, San Francisco

    San Francisco, United States

    11 h-index

    37 publications

    1.9K citations

  3. Dana-Farber Cancer Institute

    Boston, United States

    10 h-index

    39 publications

    7.8K citations

  4. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    65 publications

    6.8K citations

  5. Howard Hughes Medical Institute

    Chevy Chase, United States

    10 h-index

    15 publications

    1.7K citations

  6. Inserm

    Paris, France

    9 h-index

    45 publications

    3.4K citations

  7. Heidelberg University

    Heidelberg, Germany

    9 h-index

    30 publications

    799 citations

  8. University of Cambridge

    Cambridge, United Kingdom

    8 h-index

    40 publications

    3.2K citations

1–8 of 680

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 24 publications · 2K citations

    21

    h-index

  2. Journal of Biological Chemistry

    JBC · 16 publications · 1.7K citations

    16

    h-index

  3. PLoS ONE

    10 publications · 424 citations

    10

    h-index

  4. Nucleic Acids Research

    9 publications · 429 citations

    9

    h-index

  5. Nature Communications

    7 publications · 607 citations

    8

    h-index

1–5