Concepedia

Cell-based Toxicity Screening

Cell-Based Toxicity Screening is a methodological approach in toxicology assessment that uses living cells to evaluate the adverse effects of chemical substances, distinguished by its reliance on cellular responses as predictive indicators of toxicity.

358

Publications

21K

Citations

1.6K

Authors

568

Institutions

Publications per year

2017–2026

68

Parents

Publications

358

Toxicity Testing in the 21st Century: A Vision and a Strategy

Daniel Krewski, Daniel Acosta, Melvin E. Andersen et al. · Journal of Toxicology and Environmental Health Part B · 2010 · 1.7K citations · Full text

, , +17

A simple quantitative procedure using monolayer cultures for cytotoxicity assays (HTD/NR-90)

Ellen Borenfreund, James A. Puerner · Methods in Cell Science · 1985 · 885 citations

, , +8

A Combined Assay of Cell Viability and in Vitro Cytotoxicity with a Highly Water-Soluble Tetrazolium Salt, Neutral Red and Crystal Violet.

Munetaka Ishiyama, Hideyuki Tominaga, Masanobu Shiga et al. · Biological and Pharmaceutical Bulletin · 1996 · 733 citations · Full text

, , +12

Toxicological screening

Subramani Parasuraman · Journal of Pharmacology and Pharmacotherapeutics · 2011 · 533 citations · Full text

, , +17

The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines

Gregor Malich, Boban Markovic, Chris Winder · Toxicology · 1997 · 462 citations

, , +12

1–5 of 358

Authors

1.6K

  1. BE
    Björn Ekwall

    Uppsala University, Sweden

    11 publications · 456 citations

    11

    h-index

  2. RJ
    Richard Judson

    Environmental Protection Agency, United States

    7 publications · 728 citations

    7

    h-index

  3. KA
    Keith A. Houck

    Environmental Protection Agency, United States

    6 publications · 468 citations

    6

    h-index

  4. DM
    David M. Reif

    North Carolina State University, United States

    6 publications · 663 citations

    6

    h-index

  5. KS
    Kristin Schirmer

    Swiss Federal Institute of Aquatic Science and Technology, Switzerland

    5 publications · 406 citations

    5

    h-index

1–5 of 1.6K

Institutions

568

  1. Research Triangle Park Foundation

    Durham, United States

    15 h-index

    76 publications

    8.7K citations

  2. Environmental Protection Agency

    Washington, United States

    13 h-index

    83 publications

    8.7K citations

  3. Uppsala University

    Uppsala, Sweden

    11 h-index

    16 publications

    481 citations

  4. Joint Research Centre

    Ispra, Italy

    7 h-index

    31 publications

    1.7K citations

  5. Rockefeller University

    New York, United States

    6 h-index

    11 publications

    2.3K citations

  6. National Institutes of Health

    Bethesda, United States

    6 h-index

    36 publications

    3K citations

  7. Heidelberg University

    Heidelberg, Germany

    5 h-index

    12 publications

    386 citations

  8. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    5 h-index

    9 publications

    615 citations

1–8 of 568

Venues

  1. Toxicology in Vitro

    32 publications · 1.5K citations

    23

    h-index

  2. Toxicology Letters

    16 publications · 587 citations

    14

    h-index

  3. Toxicological Sciences

    12 publications · 1.3K citations

    12

    h-index

  4. Alternatives to Laboratory Animals

    11 publications · 330 citations

    10

    h-index

  5. PubMed

    Repository · 11 publications · 405 citations

    10

    h-index

1–5