The sensitivity and specificity of the MTS tetrazolium assay for detecting the in vitro cytotoxicity of 20 chemicals using human cell lines

Casarett and Doull's Toxicology: The Basic Science of Poisons

Annals of Internal Medicine · 1992 · 3.3K citations

Pharmacy, Pharmacology, Toxicology +11

Use of an Aqueous Soluble Tetrazolium/Formazan Assay for Cell Growth Assays in Culture

Ann H. Cory, Terence C. Owen, J. A. Barltrop et al. · Cancer Communications · 1991 · 1.5K citations

Dentistry, Pharmacology, Chemotherapy +10

5-(3-carboxymethoxyphenyl)-2-(4,5-dimethylthiazolyl)-3-(4-sulfophenyl)tetrazolium, inner salt (MTS) and related analogs of 3-(4,5-dimethylthiazolyl)-2,5-diphenyltetrazolium bromide (MTT) reducing to purple water-soluble formazans As cell-viability indicators

J. A. Barltrop, Terence C. Owen, Ann H. Cory et al. · Bioorganic & Medicinal Chemistry Letters · 1991 · 451 citations

Dentistry, Pharmacology, Drug Discovery +3

Use of an aqueous soluble tetrazolium/formazan assay to measure viability and proliferation of lymphokine-dependent cell lines

Thomas M. Buttke, James A. McCubrey, Terence C. Owen · Journal of Immunological Methods · 1993 · 324 citations

Life Sciences, Cell Biology, Immunology +6

Microculture tetrazolium assays: a comparison between two new tetrazolium salts, XTT and MTS

C. J. Goodwin, S.J. Holt, S. Downes et al. · Journal of Immunological Methods · 1995 · 237 citations

Natural Sciences, Biochemistry, Chemistry +2