Concepedia

Candidate Gene Studies

Candidate Gene Studies is a type of genetic association study that tests for statistically significant relationships between pre-specified variations in biologically plausible genes and specific traits or diseases, distinguished by its hypothesis-driven selection of candidate genes based on prior biological knowledge rather than genome-wide exploration.

727

Publications

47.9K

Citations

5.3K

Authors

1.5K

Institutions

Publications per year

2017–2026

157

Variants

Candidate Gene Association Studies

Parents

Children

Publications

727

A Genome-Wide Association Search for Type 2 Diabetes Genes in African Americans

Caitrin W. McDonough, Bong H. Roh, Maria R. Wing et al. · PLoS ONE · 2012 · 1.8K citations · Full text

, , +15

GeneMatcher: A Matching Tool for Connecting Investigators with an Interest in the Same Gene

Nara Sobreira, François Schiettecatte, David Valle et al. · Human Mutation · 2015 · 1.6K citations · Full text

, , +15

Genetic evidence equating SRY and the testis-determining factor

Philippe Berta, J Hawkins, Andrew Sinclair et al. · Nature · 1990 · 989 citations

, , +9

SFARI Gene 2.0: a community-driven knowledgebase for the autism spectrum disorders (ASDs)

Brett S. Abrahams, Dan E. Arking, Heather C. Mefford et al. · Molecular Autism · 2013 · 940 citations · Full text

, , +13

A Versatile Gene-Based Test for Genome-wide Association Studies

Jimmy Z. Liu, Allan F. McRae, Dale R. Nyholt et al. · The American Journal of Human Genetics · 2010 · 837 citations · Full text

, , +13

1–5 of 727

Authors

5.3K

  1. JI
    Jerome I. Rotter

    Harbor–UCLA Medical Center, United States

    9 publications · 702 citations

    9

    h-index

  2. PF
    Patrick F. Sullivan

    University of North Carolina at Chapel Hill, United States

    8 publications · 1.6K citations

    8

    h-index

  3. KS
    Kenneth S. Kendler

    Virginia Commonwealth University, United States

    8 publications · 1K citations

    8

    h-index

  4. ZZ
    Zhongming Zhao

    The University of Texas Health Science Center at Houston, United States

    8 publications · 401 citations

    8

    h-index

  5. HH
    Håkon Håkonarson

    Children's Hospital of Philadelphia, United States

    7 publications · 1K citations

    7

    h-index

1–5 of 5.3K

Institutions

1.5K

  1. Harvard University

    Cambridge, United States

    30 h-index

    180 publications

    15.5K citations

  2. Johns Hopkins University

    Baltimore, United States

    22 h-index

    114 publications

    16.9K citations

  3. National Institutes of Health

    Bethesda, United States

    19 h-index

    92 publications

    7.6K citations

  4. University of Pennsylvania

    Philadelphia, United States

    19 h-index

    56 publications

    6.3K citations

  5. Broad Institute

    Cambridge, United States

    18 h-index

    61 publications

    6.8K citations

  6. National Cancer Institute

    Bethesda, United States

    18 h-index

    69 publications

    6.5K citations

  7. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    18 h-index

    63 publications

    10.1K citations

  8. Inserm

    Paris, France

    17 h-index

    52 publications

    5.1K citations

1–8 of 1.5K

Venues

  1. PLoS ONE

    46 publications · 4.4K citations

    31

    h-index

  2. 17

    h-index

  3. PubMed

    Repository · 24 publications · 1K citations

    16

    h-index

  4. Genetic Epidemiology

    23 publications · 1.4K citations

    16

    h-index

  5. Bioinformatics

    15 publications · 1.1K citations

    14

    h-index

1–5