Concepedia

Broad Specificity

Broad Specificity is a type of enzyme specificity characterized by the ability of an enzyme to act on a wide range of structurally related substrates, distinguishing it from absolute or group-specific enzymes by its relatively promiscuous substrate recognition.

419

Publications

27.2K

Citations

2K

Authors

651

Institutions

Publications per year

2017–2026

54

Parents

Publications

419

Determination of bacterial load by real-time PCR using a broad-range (universal) probe and primers set

Mangala A. Nadkarni, F. Elizabeth Martin, Nicholas A. Jacques et al. · Microbiology · 2002 · 2K citations

, , +17

Efficient Neutralization of Primary Isolates of HIV-1 by a Recombinant Human Monoclonal Antibody

Dennis R. Burton, Jayashree Pyati, Raju K. Koduri et al. · Science · 1994 · 1.1K citations

, , +17

MDR1 P-Glycoprotein Is a Lipid Translocase of Broad Specificity, While MDR3 P-Glycoprotein Specifically Translocates Phosphatidylcholine

Ardy van Helvoort, Alexander J. Smith, Hein Sprong et al. · Cell · 1996 · 867 citations · Full text

, , +11

Broad diversity of neutralizing antibodies isolated from memory B cells in HIV-infected individuals

Johannes F. Scheid, Hugo Mouquet, Niklas Feldhahn et al. · Nature · 2009 · 865 citations

, , +16

Cross-Packaging of a Single Adeno-Associated Virus (AAV) Type 2 Vector Genome into Multiple AAV Serotypes Enables Transduction with Broad Specificity

Joseph E. Rabinowitz, Fabienne Rolling, Chengwen Li et al. · Journal of Virology · 2002 · 750 citations · Full text

, , +14

1–5 of 419

Authors

2K

  1. ZW
    Zhanhui Wang

    China Agricultural University, China

    7 publications · 166 citations

    7

    h-index

  2. XL
    Xiao Liang

    China Agricultural University, China

    4 publications · 86 citations

    4

    h-index

  3. JS
    Jianzhong Shen

    China Agricultural University, China

    4 publications · 99 citations

    4

    h-index

  4. HL
    Hongtao Lei

    South China Agricultural University, China

    3 publications · 74 citations

    3

    h-index

  5. JJ
    Jerome J. Perry

    North Carolina State University, United States

    3 publications · 63 citations

    3

    h-index

1–5 of 2K

Institutions

651

  1. Harvard University

    Cambridge, United States

    13 h-index

    34 publications

    3.9K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    10 h-index

    47 publications

    1.9K citations

  3. China Agricultural University

    Beijing, China

    8 h-index

    48 publications

    1.3K citations

  4. Massachusetts Institute of Technology

    Cambridge, United States

    7 h-index

    30 publications

    2.2K citations

  5. National Institutes of Health

    Bethesda, United States

    6 h-index

    12 publications

    2.2K citations

  6. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    8 publications

    1.8K citations

  7. Scripps Research Institute

    San Diego, United States

    6 h-index

    15 publications

    4K citations

  8. Monash University

    Melbourne, Australia

    6 h-index

    26 publications

    610 citations

1–8 of 651

Venues

  1. Journal of Biological Chemistry

    JBC · 24 publications · 1.7K citations

    22

    h-index

  2. Journal of Bacteriology

    JB · 22 publications · 1.2K citations

    18

    h-index

  3. European Journal of Biochemistry

    EJB · 17 publications · 1K citations

    15

    h-index

  4. Biochemical Journal

    BJ · 13 publications · 472 citations

    13

    h-index

  5. The Journal of Immunology

    JI · 11 publications · 711 citations

    12

    h-index

1–5