Structure of an HIV gp120 envelope glycoprotein in complex with the CD4 receptor and a neutralizing human antibody

Peter D. Kwong, Richard T. Wyatt, James E. Robinson, +3

Nature

Cd4 ReceptorHuman RetrovirusImmunologyAntiviral ResponseMolecular Biology +5

Antibody neutralization and escape by HIV-1

Xiping Wei, Julie M. Decker, Shuyi Wang, +12

Nature

Human RetrovirusImmunologyAntiviral ResponseAntibody NeutralizationAntibody Engineering +4

Predominant Autoantibody Production by Early Human B Cell Precursors

Hedda Wardemann, Sergey Yurasov, Anne Schaefer, +3

Science

Lymphocyte DevelopmentHumoral ResponseImmunologyBlood CellPathology +19

Efficient generation of monoclonal antibodies from single human B cells by single cell RT-PCR and expression vector cloning

Thomas Tiller, Eric Meffre, Sergey Yurasov, +3

Journal of Immunological Methods

Single Cell Rt-pcrExpression VectorImmunologyAntibody ScreeningAutoimmunity +5

Human monoclonal antibody 2G12 defines a distinctive neutralization epitope on the gp120 glycoprotein of human immunodeficiency virus type 1

Alexandra Trkola, Martin Purtscher, Thomas Muster, +7

Journal of Virology

ImmunologyMolecular BiologyAntigen ProcessingViral Structural ProteinAntibody 2G12 +14

Human Immunodeficiency Virus Type 1<i>env</i>Clones from Acute and Early Subtype B Infections for Standardized Assessments of Vaccine-Elicited Neutralizing Antibodies

Ming Li, Feng Gao, John R. Mascola, +14

Journal of Virology

Vaccine-elicited Neutralizing AntibodiesStandardized AssessmentsImmunodeficienciesImmunologyImmunotherapy +15

A conserved neutralizing epitope on gp41 of human immunodeficiency virus type 1

Thomas Muster, Franz Steindl, Martin Purtscher, +5

Journal of Virology

Conserved Neutralizing EpitopeHiv-1 Isolates MnImmunologyAntigen ProcessingViral Structural Protein +14

Broadly Neutralizing Antibodies Targeted to the Membrane-Proximal External Region of Human Immunodeficiency Virus Type 1 Glycoprotein gp41

Michael B. Zwick, Aran F. Labrijn, Meng Wang, +8

Journal of Virology

Protection of Macaques against Pathogenic Simian/Human Immunodeficiency Virus 89.6PD by Passive Transfer of Neutralizing Antibodies

John R. Mascola, Mark G. Lewis, Gabriela Stiegler, +11

Journal of Virology

Structural definition of a conserved neutralization epitope on HIV-1 gp120

Tongqing Zhou, Ling Xu, Barna Dey, +13

Nature

Virus StructureConserved Neutralization EpitopeHuman RetrovirusImmunologyAntiviral Response +6