Concepedia

Bivalent Chromatin Marks

Bivalent Chromatin Marks is a chromatin state characterized by the simultaneous presence of both activating (e.g., H3K4me3) and repressive (e.g., H3K27me3) histone post-translational modifications at the same genomic locus, typically found at promoters of developmentally regulated genes in pluripotent cells.

114

Publications

20.6K

Citations

958

Authors

342

Institutions

Publications per year

2017–2026

43

Variants

Bivalent Marks

Parents

Publications

114

A Bivalent Chromatin Structure Marks Key Developmental Genes in Embryonic Stem Cells

B Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie et al. · Cell · 2006 · 5.4K citations · Full text

, , +12

Genome-wide maps of chromatin state in pluripotent and lineage-committed cells

Tarjei S. Mikkelsen, Manching Ku, David B. Jaffe et al. · Nature · 2007 · 4.2K citations · Full text

, , +16

Chromatin signatures of pluripotent cell lines

Véronique Azuara, Pascale Perry, Stephan Sauer et al. · Nature Cell Biology · 2006 · 1.3K citations

, , +14

Human aging-associated DNA hypermethylation occurs preferentially at bivalent chromatin domains

Vardhman K. Rakyan, Thomas A. Down, Siarhei Maslau et al. · Genome Research · 2010 · 771 citations · Full text

, , +17

An Evolutionarily Conserved Function of Polycomb Silences the MHC Class I Antigen Presentation Pathway and Enables Immune Evasion in Cancer

Marian L. Burr, Christina E. Sparbier, Kah Lok Chan et al. · Cancer Cell · 2019 · 642 citations · Full text

, , +17

1–5 of 114

Authors

958

  1. PA
    Philippe Arnaúd

    Centre National de la Recherche Scientifique, France

    4 publications · 275 citations

    4

    h-index

  2. HA
    Hiroyuki Aburatani

    The University of Tokyo, Japan

    3 publications · 257 citations

    3

    h-index

  3. SB
    Stephen B. Baylin

    Johns Hopkins University, United States

    3 publications · 469 citations

    3

    h-index

  4. TK
    Tatsuhiko Kodama

    The University of Tokyo, Japan

    3 publications · 257 citations

    3

    h-index

  5. FC
    Franck Court

    Centre National de la Recherche Scientifique, France

    3 publications · 166 citations

    3

    h-index

1–5 of 958

Institutions

342

  1. Inserm

    Paris, France

    8 h-index

    42 publications

    3.6K citations

  2. Centre National de la Recherche Scientifique

    Paris, France

    8 h-index

    31 publications

    14.4K citations

  3. Harvard University

    Cambridge, United States

    8 h-index

    17 publications

    10.9K citations

  4. University of Cambridge

    Cambridge, United Kingdom

    6 h-index

    20 publications

    2.4K citations

  5. Center for Cancer Research

    Bethesda, United States

    6 h-index

    26 publications

    36.6K citations

  6. National Institutes of Health

    Bethesda, United States

    5 h-index

    27 publications

    4.5K citations

  7. Massachusetts General Hospital

    Boston, United States

    4 h-index

    13 publications

    35.9K citations

  8. Johns Hopkins University

    Baltimore, United States

    4 h-index

    18 publications

    3.6K citations

1–8 of 342

Venues

  1. Cell Reports

    8 publications · 559 citations

    8

    h-index

  2. BMC Genomics

    6 publications · 714 citations

    6

    h-index

  3. Genome Research

    GR · 6 publications · 1.5K citations

    6

    h-index

  4. Nucleic Acids Research

    6 publications · 320 citations

    6

    h-index

  5. Proceedings of the National Academy of Sciences

    PNAS · 5 publications · 511 citations

    5

    h-index

1–5