Concepedia

Biotransformation

Biotransformation is a biochemical process in which enzymes catalyze the structural modification of organic compounds, distinguishing it from physical or chemical degradation mechanisms by its reliance on biological systems to alter pollutant molecules, particularly within the context of natural attenuation.

3.9K

Publications

176.9K

Citations

15.2K

Authors

3K

Institutions

Publications per year

2017–2026

1K

Parents

Publications

3.9K

Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

Henri Duboc, Sylvie Rajca, Dominique Rainteau et al. · Gut · 2012 · 922 citations

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COMPARISON OF PRIMARY HUMAN HEPATOCYTES AND HEPATOMA CELL LINE HEPG2 WITH REGARD TO THEIR BIOTRANSFORMATION PROPERTIES

Stefan Wilkening, Frank Stahl, Augustinus Bader · Drug Metabolism and Disposition · 2003 · 771 citations

, , +17

Polycyclic aromatic hydrocarbons in sediments and mussels of the western Mediterranean sea

P. Baumard, Hélène Budzinski, Philippe Garrigues · Environmental Toxicology and Chemistry · 1998 · 692 citations

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Biotransformation of tetrachloroethylene to trichloroethylene, dichloroethylene, vinyl chloride, and carbon dioxide under methanogenic conditions

Timothy M. Vogel, Perry L. McCarty · Applied and Environmental Microbiology · 1985 · 645 citations · Full text

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Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines.

Marguerite A. Butler, M. Iwasaki, F. Peter Guengerich et al. · Proceedings of the National Academy of Sciences · 1989 · 638 citations · Full text

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1–5 of 3.9K

Authors

15.2K

  1. KF
    Kathrin Fenner

    Swiss Federal Institute of Aquatic Science and Technology, Switzerland

    29 publications · 2.2K citations

    24

    h-index

  2. JH
    Juliane Hollender

    Swiss Federal Institute of Aquatic Science and Technology, Switzerland

    16 publications · 1.4K citations

    16

    h-index

  3. AA
    Augustine Arukwe

    Norwegian University of Science and Technology, Norway

    19 publications · 891 citations

    15

    h-index

  4. SG
    Spyros G. Pavlostathis

    Georgia Institute of Technology, United States

    15 publications · 503 citations

    14

    h-index

  5. MT
    Mônica Tallarico Pupo

    Universidade de São Paulo, Brazil

    14 publications · 508 citations

    13

    h-index

1–5 of 15.2K

Institutions

3K

  1. Chinese Academy of Sciences

    Beijing, China

    41 h-index

    383 publications

    18.8K citations

  2. Swiss Federal Institute of Aquatic Science and Technology

    Dübendorf, Switzerland

    35 h-index

    186 publications

    14.8K citations

  3. ETH Zurich

    Zurich, Switzerland

    33 h-index

    110 publications

    9.6K citations

  4. Environment and Climate Change Canada

    Ottawa, Canada

    27 h-index

    82 publications

    6.8K citations

  5. Environmental Protection Agency

    Washington, United States

    26 h-index

    106 publications

    4.7K citations

  6. University of Toronto

    Toronto, Canada

    25 h-index

    101 publications

    5K citations

  7. Centre National de la Recherche Scientifique

    Paris, France

    24 h-index

    142 publications

    9.5K citations

  8. Universidade de São Paulo

    São Paulo, Brazil

    23 h-index

    155 publications

    4.9K citations

1–8 of 3K

Venues

  1. Environmental Science & Technology

    231 publications · 18.3K citations

    79

    h-index

  2. Drug Metabolism and Disposition

    147 publications · 8.5K citations

    46

    h-index

  3. Applied and Environmental Microbiology

    AEM · 84 publications · 5.8K citations

    43

    h-index

  4. Environmental Toxicology and Chemistry

    91 publications · 5.2K citations

    40

    h-index

  5. PubMed

    Repository · 148 publications · 7.3K citations

    40

    h-index

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