Concepedia

Biliary Excretion Modeling

Biliary Excretion Modeling is a computational or mathematical framework designed to quantitatively predict the hepatic clearance and biliary elimination of xenobiotics or endogenous compounds by simulating the transport, metabolism, and secretion processes specific to the hepatobiliary system.

15

Publications

491

Citations

75

Authors

26

Institutions

Publications per year

2017–2026

2

Parents

Publications

15

Prediction of Biliary Excretion in Rats and Humans Using Molecular Weight and Quantitative Structure–Pharmacokinetic Relationships

Xinning Yang, Yash Gandhi, David B. Duignan et al. · The AAPS Journal · 2009 · 126 citations · Full text

, , +16

Physicochemical Property Space of Hepatobiliary Transport and Computational Models for Predicting Rat Biliary Excretion

Manthena V. S. Varma, George Chang, Yurong Lai et al. · Drug Metabolism and Disposition · 2012 · 71 citations

, , +17

Interspecies Scaling of Biliary Excreted Drugs: A Comparison of Several Methods**The views expressed in this article are those of the author and do not reflect the official policy of the FDA. No official support or endorsement by the FDA is intended or should be inferred.

Iftekhar Mahmood · Journal of Pharmaceutical Sciences · 2005 · 48 citations

, , +17

Estimation of Biliary Excretion of Foreign Compounds Using Properties of Molecular Structure

Mohsen Sharifi, Taravat Ghafourian · The AAPS Journal · 2013 · 41 citations · Full text

, , +16

In Silico Prediction of Biliary Excretion of Drugs in Rats Based on Physicochemical Properties

Gang Luo, Stephen R. Johnson, Mei-Mann Hsueh et al. · Drug Metabolism and Disposition · 2009 · 37 citations

, , +17

1–5 of 15

Authors

75

  1. TJ
    Thomas J. Raub

    W.E. Upjohn Institute for Employment Research, United States

    1 publications · 25 citations

    1

    h-index

  2. TC
    Theunis C. Goosen

    Pfizer (United States), United States

    1 publications · 71 citations

    1

    h-index

  3. AS
    Arlene S. Bridges

    University of North Carolina at Chapel Hill, United States

    1 publications · 25 citations

    1

    h-index

  4. KA
    Koji Abe

    Tohoku University, Japan

    1 publications · 25 citations

    1

    h-index

  5. XZ
    Xinyuan Zhang

    United States Food and Drug Administration, United States

    1 publications · 11 citations

    1

    h-index

1–5 of 75

Institutions

26

  1. Pfizer (United States)

    New York, United States

    3 h-index

    8 publications

    311 citations

  2. University of California, San Francisco

    San Francisco, United States

    2 h-index

    3 publications

    85 citations

  3. Northwestern University

    Evanston, United States

    1 h-index

    2 publications

    28 citations

  4. RWTH Aachen University

    Aachen, Germany

    1 h-index

    5 publications

    65 citations

  5. Science Applications International Corporation (United States)

    McLean, United States

    1 h-index

    4 publications

    52 citations

  6. Universitätsklinikum Aachen

    Aachen, Germany

    1 h-index

    5 publications

    65 citations

  7. Tabriz University of Medical Sciences

    Tabriz, Iran

    1 h-index

    1 publications

    41 citations

  8. MRC Toxicology Unit

    Cambridge, United Kingdom

    1 h-index

    6 publications

    72 citations

1–8 of 26

Venues

  1. The AAPS Journal

    AAPSJ · 4 publications · 214 citations

    4

    h-index

  2. Drug Metabolism and Disposition

    3 publications · 133 citations

    3

    h-index

  3. Biochemical Pharmacology

    1 publications · 12 citations

    1

    h-index

  4. Biological and Pharmaceutical Bulletin

    1 publications · 12 citations

    1

    h-index

  5. Journal of Pharmaceutical Sciences

    1 publications · 48 citations

    1

    h-index

1–5