David B. Duignan

Use of Cryopreserved Human Hepatocytes in Sandwich Culture to Measure Hepatobiliary Transport

Yi‐An Bi, Diana Kazolias, David B. Duignan · Drug Metabolism and Disposition · 2006 · 212 citations

Assessment of a Micropatterned Hepatocyte Coculture System to Generate Major Human Excretory and Circulating Drug Metabolites

Wendy WeiWei Wang, Salman R. Khetani, Stacy Krzyzewski et al. · Drug Metabolism and Disposition · 2010 · 148 citations

Prediction of Biliary Excretion in Rats and Humans Using Molecular Weight and Quantitative Structure–Pharmacokinetic Relationships

Xinning Yang, Yash Gandhi, David B. Duignan et al. · The AAPS Journal · 2009 · 126 citations · Full text

Pharmacokinetic Modeling, Health Sciences, Biliary Tract +14

pH-Sensitive Interaction of HMG-CoA Reductase Inhibitors (Statins) with Organic Anion Transporting Polypeptide 2B1

Manthena V. S. Varma, Charles J. Rotter, Kevin M. Whalen et al. · Molecular Pharmaceutics · 2011 · 117 citations

Discovery of (<i>S</i>)-6-(3-Cyclopentyl-2-(4-(trifluoromethyl)-1<i>H</i>-imidazol-1-yl)propanamido)nicotinic Acid as a Hepatoselective Glucokinase Activator Clinical Candidate for Treating Type 2 Diabetes Mellitus

Jeffrey A. Pfefferkorn, Angel Guzmán-Pérez, John Litchfield et al. · Journal of Medicinal Chemistry · 2011 · 114 citations · Full text