Concepedia

Beta-sheet Rich Aggregates

Beta-Sheet Rich Aggregates is a structural class of protein assemblies characterized by a predominance of β-sheet secondary structure, distinguished from other protein aggregates by their ordered, cross-β architecture in which β-strands are oriented perpendicularly to the fibril axis, commonly associated with amyloid formation and conformational diseases.

210

Publications

17.3K

Citations

1K

Authors

365

Institutions

Publications per year

2017–2026

55

Parents

Publications

210

EGCG remodels mature α-synuclein and amyloid-β fibrils and reduces cellular toxicity

Jan Bieschke, Jenny Russ, Ralf P. Friedrich et al. · Proceedings of the National Academy of Sciences · 2010 · 1K citations · Full text

, , +17

Natural β-sheet proteins use negative design to avoid edge-to-edge aggregation

Jane S. Richardson, David Richardson · Proceedings of the National Academy of Sciences · 2002 · 773 citations · Full text

, , +15

Atomic View of a Toxic Amyloid Small Oligomer

Arthur Laganowsky, Cong Liu, M.R. Sawaya et al. · Science · 2012 · 566 citations · Full text

, , +17

β-Lactoglobulin and WPI aggregates: Formation, structure and applications

Taco Nicolaï, Michel Britten, Christophe Schmitt · Food Hydrocolloids · 2011 · 544 citations

, , +10

Sonication of proteins causes formation of aggregates that resemble amyloid

Peter B. Stathopulos, Guenter A. Scholz, Young‐Mi Hwang et al. · Protein Science · 2004 · 414 citations · Full text

, , +17

1–5 of 210

Authors

1K

  1. MS
    M.R. Sawaya

    University of California, Los Angeles, United States

    6 publications · 1.5K citations

    6

    h-index

  2. YS
    Yunxiang Sun

    Clemson University, United States

    5 publications · 155 citations

    5

    h-index

  3. FD
    Feng Ding

    Clemson University, United States

    5 publications · 155 citations

    5

    h-index

  4. DE
    David Eisenberg

    University of California, Los Angeles, United States

    5 publications · 1.4K citations

    5

    h-index

  5. KM
    Katsumi Matsuzaki

    Kyoto University, Japan

    4 publications · 317 citations

    4

    h-index

1–5 of 1K

Institutions

365

  1. University of Cambridge

    Cambridge, United Kingdom

    14 h-index

    51 publications

    3.7K citations

  2. Kyoto University

    Kyoto, Japan

    8 h-index

    45 publications

    3.1K citations

  3. Howard Hughes Medical Institute

    Chevy Chase, United States

    6 h-index

    26 publications

    9.1K citations

  4. Monash University

    Melbourne, Australia

    6 h-index

    19 publications

    866 citations

  5. Clemson University

    Clemson, United States

    6 h-index

    12 publications

    354 citations

  6. University of California, Los Angeles

    Los Angeles, United States

    5 h-index

    25 publications

    8.1K citations

  7. Ningbo University

    Ningbo, China

    5 h-index

    19 publications

    427 citations

  8. Fudan University

    Shanghai, China

    4 h-index

    15 publications

    849 citations

1–8 of 365

Venues

  1. Biochemistry

    13 publications · 1.3K citations

    13

    h-index

  2. The Journal of Physical Chemistry B

    11 publications · 322 citations

    11

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 10 publications · 3.6K citations

    10

    h-index

  4. Journal of Molecular Biology

    JMB · 9 publications · 854 citations

    9

    h-index

  5. Biophysical Journal

    8 publications · 432 citations

    8

    h-index

1–5