Concepedia

Atm Deficiency

ATM Deficiency is a genetic disorder characterized by mutations in the ATM gene, which disrupts the kinase-mediated signaling pathway essential for DNA double-strand break repair and cell cycle checkpoint control.

491

Publications

44.2K

Citations

3K

Authors

872

Institutions

Publications per year

2017–2026

94

Variants

Ataxia-telangiectasia Mutated Deficiency

Parents

Publications

491

A Single Ataxia Telangiectasia Gene with a Product Similar to PI-3 Kinase

Kinneret Savitsky, Anat Bar‐Shira, Shlomit Gilad et al. · Science · 1995 · 2.8K citations

, , +11

ATM Phosphorylates Histone H2AX in Response to DNA Double-strand Breaks

Sandeep Burma, Benjamin P. Chen, Michael Murphy et al. · Journal of Biological Chemistry · 2001 · 1.9K citations · Full text

, , +17

Atm-Deficient Mice: A Paradigm of Ataxia Telangiectasia

Carrolee Barlow, Shinji Hirotsune, Richard Paylor et al. · Cell · 1996 · 1.5K citations · Full text

, , +12

ATM Activation by Oxidative Stress

Zhi Guo, Sergei Kozlov, Martin F. Lavin et al. · Science · 2010 · 1.1K citations · Full text

, , +17

ATM and DNA-PK Function Redundantly to Phosphorylate H2AX after Exposure to Ionizing Radiation

Tom Stiff, Mark O’Driscoll, Nicole Rief et al. · Cancer Research · 2004 · 995 citations · Full text

, , +17

1–5 of 491

Authors

3K

  1. MF
    Martin F. Lavin

    The University of Queensland, Australia

    19 publications · 5.6K citations

    18

    h-index

  2. YS
    Yosef Shiloh

    Tel Aviv University, Israel

    17 publications · 6.4K citations

    17

    h-index

  3. RA
    Richard A. Gatti

    University of California, Los Angeles, United States

    17 publications · 3.8K citations

    16

    h-index

  4. CB
    Carrolee Barlow

    Salk Institute for Biological Studies, United States

    18 publications · 3.1K citations

    15

    h-index

  5. AW
    Anthony Wynshaw‐Boris

    University of California San Diego, United States

    17 publications · 3K citations

    14

    h-index

1–5 of 3K

Institutions

872

  1. National Institutes of Health

    Bethesda, United States

    28 h-index

    121 publications

    21.3K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    23 h-index

    77 publications

    14.4K citations

  3. University of California, Los Angeles

    Los Angeles, United States

    22 h-index

    82 publications

    7.6K citations

  4. Harvard University

    Cambridge, United States

    22 h-index

    78 publications

    10.5K citations

  5. Tel Aviv University

    Tel Aviv, Israel

    21 h-index

    97 publications

    49K citations

  6. QIMR Berghofer Medical Research Institute

    Brisbane, Australia

    18 h-index

    74 publications

    11.9K citations

  7. St. Jude Children's Research Hospital

    Memphis, United States

    17 h-index

    60 publications

    11.7K citations

  8. National Cancer Institute

    Bethesda, United States

    16 h-index

    75 publications

    11.9K citations

1–8 of 872

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 27 publications · 3.8K citations

    27

    h-index

  2. PubMed

    Repository · 26 publications · 2.7K citations

    22

    h-index

  3. Journal of Biological Chemistry

    JBC · 20 publications · 3.6K citations

    20

    h-index

  4. PLoS ONE

    18 publications · 618 citations

    15

    h-index

  5. Human Molecular Genetics

    16 publications · 1.3K citations

    15

    h-index

1–5