Concepedia

Arginase Deficiency

Arginase Deficiency is a rare autosomal recessive urea cycle disorder characterized by a deficiency of the enzyme arginase 1, leading to the impaired hydrolysis of arginine into ornithine and urea, resulting in hyperargininemia and progressive neurological deterioration.

382

Publications

20.1K

Citations

2K

Authors

620

Institutions

Publications per year

2017–2026

94

Parents

Publications

382

Dysregulated Arginine Metabolism, Hemolysis-Associated Pulmonary Hypertension, and Mortality in Sickle Cell Disease

Claudia R. Morris · JAMA · 2005 · 749 citations · Full text

, , +17

Differential Regulation of Nitric Oxide Synthase-2 and Arginase-1 by Type 1/Type 2 Cytokines In Vivo: Granulomatous Pathology Is Shaped by the Pattern of <scp>l</scp> -Arginine Metabolism

Matthias Hesse, Manuel Modolell, Anne Camille La Flamme et al. · The Journal of Immunology · 2001 · 681 citations · Full text

, , +17

Suppression of T-cell functions by human granulocyte arginase

Markus Munder · Blood · 2006 · 415 citations · Full text

, , +13

<i>Helicobacter pylori</i> arginase inhibits nitric oxide production by eukaryotic cells: A strategy for bacterial survival

Alain P. Gobert, David J. McGee, Mahmood Akhtar et al. · Proceedings of the National Academy of Sciences · 2001 · 374 citations · Full text

, , +13

Arginine Therapy

Claudia R. Morris, Sidney M. Morris, Ward Hagar et al. · American Journal of Respiratory and Critical Care Medicine · 2003 · 327 citations

, , +13

1–5 of 382

Authors

2K

  1. SD
    Stephen D. Cederbaum

    University of California, Los Angeles, United States

    25 publications · 1.2K citations

    21

    h-index

  2. RB
    Ruth B. Caldwell

    Augusta University, United States

    21 publications · 1K citations

    16

    h-index

  3. ZX
    Zhimin Xu

    Augusta University, United States

    12 publications · 565 citations

    12

    h-index

  4. RW
    Robert W. Caldwell

    Augusta University, United States

    13 publications · 622 citations

    11

    h-index

  5. WW
    Wayne W. Grody

    University of California, Los Angeles, United States

    10 publications · 438 citations

    10

    h-index

1–5 of 2K

Institutions

620

  1. University of California, Los Angeles

    Los Angeles, United States

    23 h-index

    145 publications

    6.6K citations

  2. Baylor College of Medicine

    Houston, United States

    16 h-index

    50 publications

    2.1K citations

  3. Augusta University

    Augusta, United States

    16 h-index

    142 publications

    5.8K citations

  4. Charlie Norwood VA Medical Center

    Augusta, United States

    12 h-index

    57 publications

    2.5K citations

  5. Augusta University Health

    Augusta, United States

    10 h-index

    70 publications

    3.9K citations

  6. University of Pittsburgh

    Pittsburgh, United States

    10 h-index

    21 publications

    3.6K citations

  7. Harvard University

    Cambridge, United States

    9 h-index

    34 publications

    2.1K citations

  8. Discovery Institute

    Seattle, United States

    9 h-index

    63 publications

    2.8K citations

1–8 of 620

Venues

  1. PubMed

    Repository · 19 publications · 510 citations

    14

    h-index

  2. PLoS ONE

    13 publications · 473 citations

    12

    h-index

  3. The Journal of Immunology

    JI · 11 publications · 1.5K citations

    11

    h-index

  4. Molecular Genetics and Metabolism

    10 publications · 413 citations

    10

    h-index

  5. The Journal of Pediatrics

    9 publications · 225 citations

    9

    h-index

1–5