Urea Cycle is a metabolic pathway that converts ammonia into urea through a series of enzyme-catalyzed reactions, primarily occurring in the liver to facilitate nitrogen excretion.
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Variants
Krebs-henseleit CycleOrnithine Cycle
Children
Allosteric Regulation Of Carbamoyl Phosphate Synthetase IAmmonia DetoxificationArginase DeficiencyArgininosuccinate Lyase DeficiencyArgininosuccinate Synthetase DeficiencyCarbamoyl Phosphate Synthetase I DeficiencyCytosolic Urea CycleHepatic Urea SynthesisInborn Errors Of Urea Cycle MetabolismMitochondrial Urea Cycle
Publications
1.3K
SIRT5 Deacetylates Carbamoyl Phosphate Synthetase 1 and Regulates the Urea Cycle
Takashi Nakagawa, David J. Lomb, Marcia C. Haigis et al. · Cell · 2009 · 779 citations · Full text
Adaptive Characteristics of Urea Cycle Enzymes in the Rat
Robert Schimke · Journal of Biological Chemistry · 1962 · 735 citations · Full text
Evolution and metabolic significance of the urea cycle in photosynthetic diatoms
Andrew E. Allen, Christopher L. Dupont, Miroslav Obornı́k et al. · Nature · 2011 · 508 citations · Full text
Life Sciences, Biochemistry, Biology +16
Comparative Biochemistry of Urea Synthesis
George W. Brown, Philip P. Cohen · Journal of Biological Chemistry · 1959 · 410 citations · Full text
Sirt3 Promotes the Urea Cycle and Fatty Acid Oxidation during Dietary Restriction
William C. Hallows, Wei Yu, Brian C. Smith et al. · Molecular Cell · 2011 · 388 citations · Full text
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University Children's Hospital Zurich
Zurich, Switzerland
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Heidelberg, Germany
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JIMD · 36 publications · 1.9K citations
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Repository · 54 publications · 1.5K citations
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