Concepedia

Antigen Processing Defects

Antigen Processing Defects is a pathological impairment in the cellular mechanism responsible for degrading and presenting antigenic peptides via major histocompatibility complex molecules, leading to aberrant immune recognition and response.

102

Publications

9.4K

Citations

560

Authors

179

Institutions

Publications per year

2017–2026

5

Parents

Publications

102

Impaired HLA Class I Antigen Processing and Presentation as a Mechanism of Acquired Resistance to Immune Checkpoint Inhibitors in Lung Cancer

Scott Gettinger, Jungmin Choi, Katherine Hastings et al. · Cancer Discovery · 2017 · 755 citations · Full text

, , +17

HLA-A2.1-Associated Peptides from a Mutant Cell Line: A Second Pathway of Antigen Presentation

Robert Henderson, Hanspeter Michel, Kazuyasu Sakaguchi et al. · Science · 1992 · 529 citations

, , +17

HLA-A2 molecules in an antigen-processing mutant cell contain signal sequence-derived peptides

Maria L. Wei, Peter Cresswell · Nature · 1992 · 500 citations

, , +15

H2-M Mutant Mice Are Defective in the Peptide Loading of Class II Molecules, Antigen Presentation, and T Cell Repertoire Selection

William Martin, Geoffrey G. Hicks, Sanjeev Kumar Mendiratta et al. · Cell · 1996 · 324 citations · Full text

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Immune Selection for Altered Antigen Processing Leads to Cytotoxic T Lymphocyte Escape in Chronic HIV-1 Infection

Rika Draenert, Sylvie Le Gall, Katja Pfafferott et al. · The Journal of Experimental Medicine · 2004 · 300 citations · Full text

, , +17

1–5 of 102

Authors

560

  1. PC
    Peter Cresswell

    Yale University, United States

    7 publications · 1.1K citations

    7

    h-index

  2. SF
    Soldano Ferrone

    Massachusetts General Hospital, United States

    6 publications · 1.3K citations

    6

    h-index

  3. KL
    Kenneth L. Rock

    University of Massachusetts Chan Medical School, United States

    5 publications · 414 citations

    5

    h-index

  4. DF
    Donald F. Hunt

    University of Virginia, United States

    4 publications · 766 citations

    4

    h-index

  5. EK
    Elizabeth K. Bikoff

    University of Oxford, United Kingdom

    4 publications · 164 citations

    4

    h-index

1–5 of 560

Institutions

179

  1. Harvard University

    Cambridge, United States

    12 h-index

    50 publications

    6.1K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    11 h-index

    44 publications

    8.8K citations

  3. National Institutes of Health

    Bethesda, United States

    9 h-index

    24 publications

    3.6K citations

  4. Yale University

    New Haven, United States

    6 h-index

    39 publications

    16.9K citations

  5. University of Washington

    Seattle, United States

    5 h-index

    11 publications

    1.3K citations

  6. Brigham and Women's Hospital

    Boston, United States

    4 h-index

    11 publications

    1.1K citations

  7. University of Virginia

    Charlottesville, United States

    4 h-index

    10 publications

    2.5K citations

  8. Massachusetts General Hospital

    Boston, United States

    4 h-index

    16 publications

    3.9K citations

1–8 of 179

Venues

  1. The Journal of Immunology

    JI · 20 publications · 956 citations

    17

    h-index

  2. The Journal of Experimental Medicine

    7 publications · 938 citations

    7

    h-index

  3. Science

    6 publications · 1.5K citations

    6

    h-index

  4. PubMed

    Repository · 6 publications · 416 citations

    6

    h-index

  5. Journal of Clinical Investigation

    JCI · 5 publications · 329 citations

    5

    h-index

1–5