Concepedia

Antibody Maturation

Antibody Maturation is a biological process in adaptive immunity characterized by the refinement of antibody specificity and affinity through somatic hypermutation and class-switch recombination in B cells following antigen exposure.

514

Publications

32.2K

Citations

3.1K

Authors

795

Institutions

Publications per year

2017–2026

126

Parents

Publications

514

Defective B cell tolerance checkpoints in systemic lupus erythematosus

Sergey Yurasov, Hedda Wardemann, Johanna Hammersen et al. · The Journal of Experimental Medicine · 2005 · 700 citations · Full text

, , +17

Antigen recognition strength regulates the choice between extrafollicular plasma cell and germinal center B cell differentiation

Didrik Paus, Tri Giang Phan, Tyani D. Chan et al. · The Journal of Experimental Medicine · 2006 · 541 citations · Full text

, , +17

Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease

María Florencia Delgado, Silvina Coviello, Ana C. Monsalvo et al. · Nature Medicine · 2008 · 498 citations · Full text

, , +16

Visualizing antibody affinity maturation in germinal centers

Jeroen M. J. Tas, Luka Mesin, Giulia Pasqual et al. · Science · 2016 · 494 citations · Full text

, , +17

Developmental aspects of antibody formation and structure

Felix Haurowitz · Immunochemistry · 1972 · 477 citations

, , +14

1–5 of 514

Authors

3.1K

  1. SK
    Surender Khurana

    Center for Biologics Evaluation and Research, United States

    12 publications · 981 citations

    12

    h-index

  2. HG
    Hana Golding

    Center for Biologics Evaluation and Research, United States

    10 publications · 629 citations

    10

    h-index

  3. MC
    Michel C. Nussenzweig

    Rockefeller University, United States

    9 publications · 1.4K citations

    9

    h-index

  4. TB
    Thomas B. Kepler

    Duke University, United States

    9 publications · 976 citations

    9

    h-index

  5. BF
    Barton F. Haynes

    Duke University, United States

    9 publications · 536 citations

    9

    h-index

1–5 of 3.1K

Institutions

795

  1. National Institutes of Health

    Bethesda, United States

    24 h-index

    169 publications

    9.8K citations

  2. Howard Hughes Medical Institute

    Chevy Chase, United States

    23 h-index

    64 publications

    9.2K citations

  3. Harvard University

    Cambridge, United States

    22 h-index

    88 publications

    5.3K citations

  4. National Institute of Allergy and Infectious Diseases

    Bethesda, United States

    21 h-index

    154 publications

    7.5K citations

  5. Rockefeller University

    New York, United States

    15 h-index

    109 publications

    12.1K citations

  6. National Cancer Institute

    Bethesda, United States

    14 h-index

    55 publications

    3.5K citations

  7. MRC Laboratory of Molecular Biology

    Cambridge, United Kingdom

    13 h-index

    34 publications

    4K citations

  8. Center for Biologics Evaluation and Research

    Silver Spring, United States

    12 h-index

    60 publications

    4.7K citations

1–8 of 795

Venues

  1. The Journal of Immunology

    JI · 40 publications · 2.2K citations

    25

    h-index

  2. The Journal of Experimental Medicine

    29 publications · 3.6K citations

    24

    h-index

  3. Proceedings of the National Academy of Sciences

    PNAS · 23 publications · 1.9K citations

    21

    h-index

  4. PubMed

    Repository · 27 publications · 784 citations

    19

    h-index

  5. European Journal of Immunology

    EJI · 29 publications · 994 citations

    18

    h-index

1–5