Concepedia

Antibody Fc Libraries

Antibody Fc Libraries is a methodological framework in protein engineering that consists of systematically diversified populations of antibody Fc regions designed to enable high-throughput screening and selection of variants with enhanced effector functions, stability, or pharmacokinetic properties.

15

Publications

698

Citations

127

Authors

36

Institutions

Publications per year

2017–2026

3

Parents

Publications

15

Introducing antigen-binding sites in structural loops of immunoglobulin constant domains: Fc fragments with engineered HER2/neu-binding sites and antibody properties

Gordana Wozniak‐Knopp, Stefan Bartl, Anna Bauer et al. · Protein Engineering Design and Selection · 2010 · 122 citations · Full text

, , +17

In Vivo Neutralization of α-Cobratoxin with High-Affinity Llama Single-Domain Antibodies (VHHs) and a VHH-Fc Antibody

Gabrielle Richard, Ashley J. Meyers, Michael D. McLean et al. · PLoS ONE · 2013 · 117 citations · Full text

, , +17

The change of the scFv into the Fab format improves the stability and in vivo toxin neutralization capacity of recombinant antibodies

Verónica Quintero‐Hernández, Víctor Rivelino Juárez-González, Mauricio Ortíz-León et al. · Molecular Immunology · 2006 · 94 citations

, , +15

A Fc engineering approach to define functional humoral correlates of immunity against Ebola virus

Bronwyn M. Gunn, Richard Lu, Matthew D. Slein et al. · Immunity · 2021 · 67 citations · Full text

, , +17

Generation of a panel of related human scFv antibodies with high affinities for human CEA

Jane Osbourn, Anne W Field, Jane Wilton et al. · Immunotechnology · 1996 · 49 citations

, , +14

1–5 of 15

Authors

127

  1. CL
    Claudia Langermann

    Wehrwissenschaftliche Institut für Schutztechnologien, Germany

    1 publications · 32 citations

    1

    h-index

  2. YK
    Yong‐Sung Kim

    Ajou University, South Korea

    2 publications · 38 citations

    1

    h-index

  3. LK
    Lansana Kanneh

    Tulane University, United States

    1 publications · 67 citations

    1

    h-index

  4. JL
    Janita Lövgren

    University of Turku, Finland

    1 publications · 13 citations

    1

    h-index

  5. RS
    Rosalba Sánchez

    Universidad Nacional Autónoma de México, Mexico

    1 publications · 94 citations

    1

    h-index

1–5 of 127

Institutions

36

  1. University of Siegen

    Siegen, Germany

    1 h-index

    4 publications

    192 citations

  2. University of Pittsburgh Medical Center

    Pittsburgh, United States

    1 h-index

    1 publications

    22 citations

  3. Scripps Research Institute

    San Diego, United States

    1 h-index

    2 publications

    134 citations

  4. Turku Centre for Biotechnology

    Turku, Finland

    1 h-index

    5 publications

    65 citations

  5. Wehrwissenschaftliche Institut für Schutztechnologien

    Münster, Germany

    1 h-index

    2 publications

    64 citations

  6. LFB (United States)

    Framingham, United States

    1 h-index

    9 publications

    432 citations

  7. University of Freiburg

    Freiburg im Breisgau, Germany

    1 h-index

    2 publications

    86 citations

  8. Technische Universität Braunschweig

    Braunschweig, Germany

    1 h-index

    5 publications

    160 citations

1–8 of 36

Venues

  1. mAbs

    2 publications · 80 citations

    2

    h-index

  2. Journal of Biological Chemistry

    JBC · 2 publications · 35 citations

    2

    h-index

  3. PLoS ONE

    2 publications · 136 citations

    2

    h-index

  4. Immunity

    1 publications · 67 citations

    1

    h-index

  5. International Journal of Molecular Sciences

    IJMS · 1 publications · 22 citations

    1

    h-index

1–5